CDCP1 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPK-01256

Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 73.2 kDa and the accession number is F6TPM5.

CDCP1 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPK-01256

规格	价格	库存
100 μg	¥ 3,400	5日内发货
500 μg	¥ 13,600	5日内发货
1 mg	¥ 22,700	5日内发货

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产品信息

生物活性	Immobilized Cynomolgus CDCP1 at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 17.5ng/ml determined by ELISA.
产品描述	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 73.2 kDa and the accession number is F6TPM5.
种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	F6TPM5
别名	UNQ2486,TRASK,SIMA135,PRO5773,CDCP1,CD318
蛋白构建	Ala29-Thr667
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	73.2 kDa (predicted). Due to glycosylation, the protein migrates to 80-115 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.