IL-18RAP Protein, Human, Recombinant (hFc & His)

产品编号 TMPJ-00344

IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

IL-18RAP Protein, Human, Recombinant (hFc & His)

产品编号 TMPJ-00344

规格	价格	库存
10 μg	¥ 380	5日内发货
50 μg	¥ 1,170	5日内发货
500 μg	¥ 8,600	5日内发货
1 mg	¥ 12,800	5日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc-6xHis
蛋白编号	O95256
别名	Interleukin-18 receptor β,Interleukin-18 receptor beta,Interleukin-18 receptor accessory protein-like,Interleukin-18 receptor accessory protein,Interleukin-1 receptor 7,IL-1R accessory protein-like,IL18RAP,CDw218b,CD218 antigen-like family member B,C,Accessory protein-like
氨基酸序列	Phe20-Arg356
蛋白构建	Phe20-Arg356
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	88 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

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