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Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 50.4 kDa and the accession number is Q9NYJ7-1.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μg | ¥ 2,960 | 5日内发货 | |
500 μg | ¥ 11,800 | 5日内发货 | |
1 mg | ¥ 19,700 | 5日内发货 |
生物活性 | 1. Immobilized Human DLL3, His Tag at 0.1μg/mL (100μl/well). Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA (QC Test).
2. Anti-DLL3 Antibody captured on CM5 Chip via Protein A can bind Human DLL3, His Tag with an affinity constant of 0.22 nM as determined in SPR assay. |
产品描述 | Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 50.4 kDa and the accession number is Q9NYJ7-1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | N-His |
蛋白编号 | Q9NYJ7-1 |
别名 | δ3,SCDO1δ3,SCDO1delta3,SCDO1,Pudgy,DLL3,Delta3 |
蛋白构建 | Ala27-Arg490 |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | 50.4 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result. |
内毒素 | < 1 EU/μg by the LAL method. |
缓冲液 | Supplied as 0.22 μm filtered solution in 20 mM PB, 50 mM NaCl, 10% Glycerol (pH 8.0). |
存储 | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). |
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