RAS inhibitor Abd-7

Name: RAS inhibitor Abd-7
Brand: TargetMol
SKU: T36641
Price: 198 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T36641Cas号 2351843-48-4

RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders RAS-effector interactions and suppresses endogenous RAS-dependent signaling. Additionally, RAS inhibitor Abd-7 disrupts the PPI of different mutant KRAS proteins with PI3K, CRAF, RALGDS, as well as NRAS Q61H and HRAS G12V[1].

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RAS inhibitor Abd-7

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产品编号 T36641Cas号 2351843-48-4

规格	价格	库存
2 mg	¥ 1,710	5日内发货
5 mg	¥ 2,890	5日内发货
25 mg	¥ 9,160	6-8周
50 mg	¥ 11,900	6-8周
100 mg	¥ 17,500	6-8周
1 mL x 10 mM (in DMSO)	¥ 3,180	5日内发货

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TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

产品介绍

生物活性

产品描述

体外活性

RAS inhibitor Abd-7 (0-20 μM; 24-48 hours) is a cell-potent inhibitor affecting the viability of cancer cell lines in a single digit to low micromolar range[1].

化学信息

分子量	391.46
分子式	C₂₃H₂₅N₃O₃
CAS No.	2351843-48-4

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 125 mg/mL (319.32 mM), Sonication is recommended.

H2O: < 0.1 mg/mL (insoluble)

溶液配制表

	1mg	5mg	10mg	50mg
1 mM	2.5545 mL	12.7727 mL	25.5454 mL	127.7270 mL
5 mM	0.5109 mL	2.5545 mL	5.1091 mL	25.5454 mL
10 mM	0.2555 mL	1.2773 mL	2.5545 mL	12.7727 mL
20 mM	0.1277 mL	0.6386 mL	1.2773 mL	6.3863 mL
50 mM	0.0511 mL	0.2555 mL	0.5109 mL	2.5545 mL
100 mM	0.0255 mL	0.1277 mL	0.2555 mL	1.2773 mL