LRP-6 Protein, Human, Recombinant (mFc)

产品编号 TMPK-00744

Low-density lipoprotein receptor protein 6 (LRP6) is a Wnt co-receptor with essential functions in the Wnt/β-catenin pathway, and mutations in LRP6 gene are linked to many complex human diseases, including metabolic syndrome, cancer, Alzheimer's disease and osteoporosis. LRP-6 interacts closely with PDGF receptor β and TGF-β receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT/β-catenin. LRP-6 Protein, Human, Recombinant (mFc) is expressed in HEK293 Cells. The accession number is O75581-1.

LRP-6 Protein, Human, Recombinant (mFc)

产品编号 TMPK-00744

规格	价格	库存
100 μg	¥ 2,360	5日内发货
500 μg	¥ 9,490	5日内发货
1 mg	¥ 15,800	5日内发货

大包装 & 定制

加入购物车

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

资源下载

重组蛋白用户指南

产品信息

生物活性	Immobilized Human DKK1, His Tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 0.58 μg/mL determined by ELISA. Immobilized Human SOST, His Tag at 2 μg/mL (100 μL/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 13.1 ng/mL determined by ELISA. Immobilized Human LRP-6, mFc Tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for Human R spondin 1, His Tag with the EC50 of 4.4 μg/mL determined by ELISA.
产品描述	Low-density lipoprotein receptor protein 6 (LRP6) is a Wnt co-receptor with essential functions in the Wnt/β-catenin pathway, and mutations in LRP6 gene are linked to many complex human diseases, including metabolic syndrome, cancer, Alzheimer's disease and osteoporosis. LRP-6 interacts closely with PDGF receptor β and TGF-β receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT/β-catenin. LRP-6 Protein, Human, Recombinant (mFc) is expressed in HEK293 Cells. The accession number is O75581-1.
种属	Human
表达系统	HEK293 Cells
标签	C-mFc (IgG2a)
蛋白编号	O75581-1
别名	LRP-6,LRP6,FLJ90421,FLJ90062,DCAD2
蛋白构建	Ala20-Pro630
蛋白纯度	> 90% as determined by Tris-Bis PAGE
分子量	95.32 kDa (predicted); 97-110 kDa (Bis-Tris PAGE, due to glycosylation)
内毒素	< 1 EU/μg by the LAL method.
缓冲液	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Low-density lipoprotein receptor protein 6 (LRP6) is a Wnt co-receptor with essential functions in the Wnt/β-catenin pathway, and mutations in LRP6 gene are linked to many complex human diseases, including metabolic syndrome, cancer, Alzheimer's disease and osteoporosis. LRP-6 interacts closely with PDGF receptor β and TGF-β receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT/β-catenin.