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Perforin-1/PRF1 Protein, Human, Recombinant (His & MBP)

Perforin-1/PRF1 Protein, Human, Recombinant (His & MBP)

产品编号 TMPH-01853
别名: Perforin-1, PRF1, Lymphocyte pore-forming protein, Cytolysin

Perforin-1/PRF1 Protein, Human, Recombinant (His & MBP) is expressed in Baculovirus insect cells with N-MBP and C-6xHis tag. The predicted molecular weight is 103.2 kDa and the accession number is P14222.

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Perforin-1/PRF1 Protein, Human, Recombinant (His & MBP)
规格 价格/CNY 货期 数量
20 μg ¥ 3,120 20日内发货
100 μg ¥ 8,760 20日内发货
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产品目录号及名称: Perforin-1/PRF1 Protein, Human, Recombinant (His & MBP) (TMPH-01853)
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产品描述 Perforin-1/PRF1 Protein, Human, Recombinant (His & MBP) is expressed in Baculovirus insect cells with N-MBP and C-6xHis tag. The predicted molecular weight is 103.2 kDa and the accession number is P14222.
种属 Human
表达系统 Baculovirus Insect Cells
标签 N-MBP, C-6xHis
蛋白编号 P14222
别名 Perforin-1, PRF1, Lymphocyte pore-forming protein, Cytolysin
氨基酸序列 PCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFPVDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARDAARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREALRRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQMLLGEPPGNRSGAVW
蛋白构建 22-555 aa
蛋白纯度 > 85% as determined by SDS-PAGE.
分子量 103.2 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Pore-forming protein that plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

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Keywords

Perforin-1/PRF1 Protein, Human, Recombinant (His & MBP) Perforin-1 PRF1 Lymphocyte pore-forming protein Cytolysin recombinant recombinant-proteins proteins protein

 

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