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(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively).
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 μg | ¥ 1,190 | 35日内发货 | |
1 mg | ¥ 2,270 | 35日内发货 | |
5 mg | ¥ 9,360 | 35日内发货 | |
10 mg | ¥ 16,300 | 35日内发货 |
产品描述 | (S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively). |
别名 | (S)-p38 MAPK Inhibitor III |
分子量 | 404.5 |
分子式 | C23H21FN4S |
CAS No. | 581098-48-8 |
密度 | 1.30 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | DMSO: 12 mg/mL Ethanol: 30 mg/mL Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/mL DMF: 20 mg/mL |
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