LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 24-458, hFc)

产品编号 TMPK-01109

LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 24-458, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q8NHL6-1.

LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 24-458, hFc)

产品编号 TMPK-01109

LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 24-458, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q8NHL6-1.

规格	价格	库存
100 μg	¥ 1,990	5日内发货
500 μg	¥ 8,000	5日内发货
1 mg	¥ 13,300	5日内发货

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产品信息

生物活性	1. Immobilized Human LILRB1, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-LILRB1 Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA. 2. Human LILRB1, hFc Tag captured on Protein A Chip can bind Human HLA-G Tetramer, His Tag with an affinity constant of 1.49nM as determined in SPR assay.
产品描述	LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 24-458, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q8NHL6-1.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q8NHL6-1
别名	XXbac-BCX85G21.4,MIR7,LIR1,LILRB1,ILT2FLJ37515,ILT-2,ILT2,CD85J
蛋白构建	Gly24-His458
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	73.8 kDa (predicted). Due to glycosylation, the protein migrates to 78-105 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response.