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PD-1-IN-25 (compound 43) 是一种抑制PD-1/PD-L1相互作用的有效化合物,在HTRF测定中显示出10.2 nM的IC50值。此化合物能够阻断PD-1/PD-L1细胞信号传导途径,进而促进CD8+ T细胞的活化,并有效延缓肿瘤生长。
PD-1-IN-25 (compound 43) 是一种抑制PD-1/PD-L1相互作用的有效化合物,在HTRF测定中显示出10.2 nM的IC50值。此化合物能够阻断PD-1/PD-L1细胞信号传导途径,进而促进CD8+ T细胞的活化,并有效延缓肿瘤生长。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | PD-1-IN-25 (compound 43) serves as a powerful inhibitor of the PD-1/PD-L1 interaction, boasting an impressive IC50 of 10.2 nM, as measured in the HTRF assay. By impeding PD-1/PD-L1 cellular signaling, PD-1-IN-25 facilitates the activation of CD8+ T cells. Furthermore, it has been shown to delay tumor growth [1]. |
分子量 | 725.13 |
分子式 | C37H35ClF2N2O9 |
CAS No. | 2413100-40-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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