Cholecystokinin Receptor

Cholecystokinin (CCK) receptors are G protein-coupled receptors (GPCRs) that bind to the peptide hormone cholecystokinin. There are two main types of CCK receptors: CCK1 (also known as CCK-A) and CCK2 (also known as CCK-B). CCK1 receptors are mainly found in the gastrointestinal tract and pancreas, where they regulate bile secretion, enzyme release, and gastric motility. CCK2 receptors are primarily located in the brain and stomach, influencing functions such as anxiety, pain perception, and gastric acid secretion. Activation of these receptors plays a crucial role in digestion and regulating satiety.