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Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μg | ¥ 3,170 | 现货 |
生物活性 | The specific activity was determined to be >30 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate. |
产品描述 | Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury. |
种属 | Human |
表达系统 | Baculovirus Insect Cells |
标签 | N-His |
蛋白编号 | Q9Y6E0-2 |
别名 | STK3,STE20,serine/threonine kinase 24,RP11-111L24.5,MST3B,MST3,HEL-S-95 |
蛋白构建 | A DNA sequence encoding the human STK24 isoform A (Q9Y6E0-2) (Met 1-His 431) was expressed, with a polyhistidine tag at the N-terminus. Predicted N terminal: Met |
蛋白纯度 | > 82 % as determined by SDS-PAGE |
分子量 | 50.3 kDa (predicted); 55 kDa (reducing conditions) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Supplied as sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 20% gly, 0.1 mM EGTA, 0.1 mM EDTA, 0.25 mM DTT. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. |
研究背景 | Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury. |
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