肿瘤

1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合，用于肿瘤相关的研究以及抗肿瘤药物的筛选，用于高通量、高内涵筛选；

523 种靶向肿瘤免疫治疗靶点的小分子，可用于高通量和高内涵筛选，是研究肿瘤免疫治疗的有力工具；

210 种泛素化相关的小分子，用于高通量和高内涵筛选；

48 个肿瘤化疗药物，可以用于高通量和高内涵筛选；

76 种外泌体相关的化合物，可以用于高通量和高内涵筛选；

2545 个具有抗癌活性小分子的独特集合，可用于高通量高内涵筛选。

8700 种肿瘤相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；

2103 种与肺癌相关的化合物，可以用于抗肺癌药物研发和药理研究；

3580 种具有抗肿瘤活性的化合物的特有集合，用于高通量、高内涵筛选；

667 种 DNA 损伤 修复靶向、结构新颖的化合物；

119 个肿瘤靶向治疗药物，可以用于高通量和高内涵筛选；

142 种靶向微管的分子集合，用于高通量筛选和高内涵筛选；

1040 个与 DNA 损伤和修复紧密相关的化合物集合，是高通量筛选，高内涵筛选的良好载体；

1779 个具有抗癌活性小分子的独特集合，所有化合物都经过了严格的临床前研究和临床试验，由FDA、EMA 或NMPA 批准上市，可用于高通量、高内涵筛选。

1867 种与卵巢癌相关的化合物，可以用于抗卵巢癌药物研发和药理研究

2440 种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；

The total number of compounds in the Aurora B Kinase Targeted Library is about 1,000.

OTAVAchemicals offers a high-quality PDZ Domain Targeted Library.

OTAVAchemicals offers Enhancer of Zeste Homolog 2 (EZH2) Targeted Library. It contains 979 compounds with predicted inhibitory activity against this enzyme.

ChemDiv’s Antimitotic Tubulin Library contains 18,000 compounds.

Mitogen-activated protein kinase 1 (MAPK1 ERK2) inhibitor library contains 197 compounds.

The Life Chemicals Receptor-based Screening Library contains over 2,000 potential lysine-specific demethylase 4A (KDM4A) inhibitors selected with computational chemistry and virtual screening techniques. The Library presented is a rich source of inhibitors for screening projects in KDM-related drug discovery.

Life Chemicals has designed a Library of over 3,900 drug-like screening compounds that are small-molecule analogs of known ligase inhibitors with experimentally determined activity.

We have designed an MDM2-targeted library of more than 23K small molecule compounds.

Targeted Oncology Library contains 4815 compounds

Tubulin Inhibitors library in UORSY contains 2003 compounds.

ADK Focused Library in the Princeton BioMolecal Research contains 146 compounds.

Bromodomain-containing protein 4 (BRD4) inhibitor library contains 401 compounds.

2000 种与肝癌相关的化合物，可以用于抗肝癌药物研发和药理研究；

1880 种与结直肠癌相关的化合物，可以用于高通量和高内涵筛选；

微管蛋白库包含3200个化合物。

DCAFs靶向配体库包含5440种化合物，这些化合物有可能充当分子胶。

ChemDiv’s KRAS-Targeted Library contains 11,000 compounds.

ChemDiv’s BRD4 Targeted Library contains 5,000 compounds.

OTAVAchemicals offers a Lysine-specific demethylase 4C (GASC1) Targeted Library. It contains 966 compounds with predicted inhibitory activity against this enzyme.

CDK Focused Library in the Princeton BioMolecal Research contains 1483 compounds.

OTAVAchemicals offers Matrix metalloproteinase-2 Targeted Library (726 compounds).

3150 个具有抗癌活性小分子的独特集合，生物活性已经临床前实验证实，可用于高通量、高内涵筛选；

Proto-oncogene tyrosine protein kinase Kit inhibitor library in Otava contains 214 compounds

ChemDiv 的Aurora A-B Kinases 库包含10,000种化合物。 Aurora 激酶是一类丝氨酸 苏氨酸激酶家族，包括Aurora A (AURKA)、Aurora B (AURKB)和Aurora C (AURKC)。它们对细胞分裂至关重要，通过调节有丝分裂特别是染色体分离过程来实现。除了调节有丝分裂，Aurora 激酶还参与调节减数分裂。

ChemDiv 的 Akt 靶向库包含15,000种化合物。Akt 激酶，也被称为蛋白激酶 B（PKB），是扩展的丝氨酸 苏氨酸蛋白激酶家族的关键成员之一。该激酶在多个细胞过程中起着关键作用，如葡萄糖代谢、细胞增殖、凋亡、转录和细胞迁移。

P21-activated kinase 1 (PAK1) inhibitor library in Otava contains 606 compounds.

Hippo Pathway Modulators Library in UORSY contains 2608 compounds.

Cyclin-dependent kinase 2 (CDK2) inhibitor library contains 670 compounds.

OTAVAchemicals DOT1L Targeted Library (622 compounds) has been carefully designed with a receptor-based approach that included docking of Drug-like Green Collection in the active site of human DOT1L (crystal structure of the complex with inhibitor FED2, PDB ID 4EQZ)