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PAR2 (1-6) amide (human) (trifluoroacetate salt)
还可以产品编号 T35955Cas号 2379569-17-0
别名 PAR2 (1-6) amide (human) (trifluoroacetate salt)
PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide production and degranulation in isolated human eosinophils when used at a concentration of 500 μM.3PAR2 (1-6) amide (5 μmol/kg) induces tear secretion in rats when used in combination with amastatin .4
PAR2 (1-6) amide (human) (trifluoroacetate salt)
还可以产品编号 T35955 别名 PAR2 (1-6) amide (human) (trifluoroacetate salt)Cas号 2379569-17-0
PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide production and degranulation in isolated human eosinophils when used at a concentration of 500 μM.3PAR2 (1-6) amide (5 μmol/kg) induces tear secretion in rats when used in combination with amastatin .4
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥ 1,080 | 35日内发货 | |
| 10 mg | ¥ 1,970 | 35日内发货 | |
| 25 mg | ¥ 4,180 | 35日内发货 | |
| 50 mg | ¥ 7,840 | 35日内发货 |
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| 产品描述 | PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide production and degranulation in isolated human eosinophils when used at a concentration of 500 μM.3PAR2 (1-6) amide (5 μmol/kg) induces tear secretion in rats when used in combination with amastatin .4 |
| 别名 | PAR2 (1-6) amide (human) (trifluoroacetate salt) |
| 分子量 | 728.812 |
| 分子式 | C30H55F3N8O9 |
| CAS No. | 2379569-17-0 |
储存&溶解度
| 存储 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度信息 | Ethanol: 5 mg/mL DMF: 30 mg/mL DMSO: 15 mg/mL PBS (pH 7.2): 10 mg/mL |
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