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Tubulin inhibitor 16 是有效的微管蛋白抑制剂,具有抗增殖活性。Tubulin inhibitor 16 在 HepG2 细胞中表现出细胞毒性。
Tubulin inhibitor 16 是有效的微管蛋白抑制剂,具有抗增殖活性。Tubulin inhibitor 16 在 HepG2 细胞中表现出细胞毒性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 10-14周 | |
50 mg | ¥ 13,800 | 10-14周 | |
100 mg | ¥ 17,500 | 10-14周 |
产品描述 | Tubulin inhibitor 16 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 16 exhibits cytotoxicity in HepG2 cells [1]. |
体外活性 | Tubulin inhibitor 16 (compound 2) (0-25 μM, 24 h followed by a 72 h compound-free incubation period) exhibits antiproliferative activity with IC 50 s of 1.43, 0.19, 2.33, 0.58, 0.83, 0.20, >25 μM for MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116, THLE-3 cells [1]. Cell Proliferation Assay [1] Cell Line: MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116 cells Concentration: 0-50 μM Incubation Time: 96 h Result: Exhibited antiproliferative activity with IC 50 s of 0.75, 0.17, 3.12, 0.41, 0.37, 0.22 μM for MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116 cells, respectively. Cell Cytotoxicity Assay [1] Cell Line: HepG2 cells Concentration: 0.5, 1 μM Incubation Time: 14 days Result: No colonies were evident when cells were treated with 0.5 or 1 μM. |
分子量 | 269.27 |
分子式 | C16H12FNO2 |
存储 | Shipping with blue ice. |
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