LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep)

产品编号 TMPY-07172

LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is O75473.

LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep)

产品编号 TMPY-07172

LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is O75473.

规格	价格	库存
20 μg	¥ 4,920	期货
100 μg	¥ 9,870	期货
500 μg	¥ 36,500	期货

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产品信息

生物活性	Immobilized LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep) (Cat#TMPY-07172) at 5 μg/mL (100 μL/well) can bind Petosemtamab Derived Anti-CCR5 Monoclonal antibody, Human IgG1, the EC50 is 1.5-5 ng/mL.
产品描述	LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is O75473.
种属	Human
表达系统	HEK293 Cells
标签	N-Flag, C-His-Strep
蛋白编号	O75473
别名	HG38,GRP49,GPR67,GPR49,FEX
蛋白构建	A DNA sequence encoding the Human LGR5 -VLP (O75473) (Gly22-Ser844) was expressed, with a Flag tag at the N-terminus, a polyhistidine tag and a strep tag at the C-terminus.
分子量	95.01 kDa (predicted)
内毒素	< 1.0 EU per μg protein as determined by the LAL method.
缓冲液	Supplied as sterile 50 mM Hepes, 150 mM NaCl, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
存储	Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
运输方式	It is supplied and shipped as liquid with dry ice.
研究背景	Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) plays a vital role in the development of malignant tumors. Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) is highly expressed in colorectal tumors and marks colon cancer stem cells that drive tumor growth and metastasis. LGR5, a well-characterized marker of stem cell and cancer stem cells (CSCs), is best known as a transmembrane receptor for increases canonical Wnt signaling amplitude. LGR5 expressing cells are not limited to the postulated stem cell niche but LGR5 expression is hormonally regulated.

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