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CPT

Carnitine palmitoyltransferase I (CPT1) also known as carnitine acyltransferase I, CPTI, CAT1, CoA:carnitine acyl transferase (CCAT), or palmitoylCoA transferase I, is a mitochondrial enzyme responsible for the formation of acyl carnitines by catalyzing the transfer of the acyl group of a long-chain fatty acyl-CoA from coenzyme A to l-carnitine. The product is often Palmitoylcarnitine (thus the name), but other fatty acids may also be substrates. It is part of a family of enzymes called carnitine acyltransferases. This "preparation" allows for subsequent movement of the acyl carnitine from the cytosol into the intermembrane space of mitochondria.

Etomoxir
T4535L124083-20-1
Etomoxir 是肉碱棕榈酰转移酶 1a (CPT-1a) 抑制剂,通过抑制 CPT-1a 来抑制脂肪酸氧化,且抑制人、大鼠和豚鼠中棕榈酸酯的氧化。Etomoxir 对腺嘌呤核苷酸转位酶有抑制作用,可通过破坏CoA稳态来抑制巨噬细胞极化。
  • ¥ 281
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TargetMol | Inhibitor Hot
McN3716
T1197869207-52-9In house
McN3716 是一种肉碱棕榈酰转移酶 I (CPT-1) 抑制剂,可用于研究代谢疾病。
  • ¥ 2350
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