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m-PEG6-thiol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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m-PEG6-thiol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 133 | 5日内发货 | |
5 mg | ¥ 192 | 5日内发货 | |
10 mg | ¥ 263 | 5日内发货 | |
25 mg | ¥ 418 | 5日内发货 | |
100 mg | 询价 | 5日内发货 |
产品描述 | m-PEG6-thiol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
分子量 | 312.42 |
分子式 | C13H28O6S |
CAS No. | 441771-60-4 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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