购物车
- 全部删除
- 您的购物车当前为空
hCAIX/XII-IN-1 是一种有效的CAIX/XII 抑制剂,KI 值分别为 0.48 μM 和 0.83 μM。hCAIX/XII-IN-1 显示出体外抗增殖活性。hCAIX/XII-IN-1 诱导 MCF-7 细胞凋亡apoptosis。
hCAIX/XII-IN-1 是一种有效的CAIX/XII 抑制剂,KI 值分别为 0.48 μM 和 0.83 μM。hCAIX/XII-IN-1 显示出体外抗增殖活性。hCAIX/XII-IN-1 诱导 MCF-7 细胞凋亡apoptosis。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 10-14周 | |
50 mg | ¥ 13,800 | 10-14周 | |
100 mg | ¥ 17,500 | 10-14周 |
产品描述 | hCAIX/XII-IN-1, a potent inhibitor of both CAIX and CAXII, exhibits KI values of 0.48 μM for CAIX and 0.83 μM for CAXII, respectively. This compound demonstrates antiproliferative activity in vitro and induces apoptosis in MCF-7 cells [1]. |
体外活性 | hCAIX/XII-IN-1 (compound 11a) (3.125, 6.25, 12.5, 25, 50 μM, 48 h) shows antiproliferative activity with an IC 50 value of 0.48 μM in MCF-7 cells [1]. hCAIX/XII-IN-1 (0.48 μM; 24 h) increases the cell populations of Sub-G1 phase [1]. hCAIX/XII-IN-1 (0.48 μM) induces apoptosis in MCF-7 cells [1]. Cell Proliferation Assay [1] Cell Line: MCF-7 cells Concentration: 3.125, 6.25, 12.5, 25, 50 μM Incubation Time: 48 h Result: Showed antiproliferative activity with an IC 50 value of 0.48 μM in MCF-7 cells. Cell Cycle Analysis [1] Cell Line: MCF-7 cells Concentration: 0.48 μM Incubation Time: 24 h Result: Significantly increased the cell populations of Sub-G1 phase. Apoptosis Analysis [1] Cell Line: MCF-7 cells Concentration: 0.48 μM Incubation Time: Result: Induced apoptosis in MCF-7 cells. |
分子量 | 397.42 |
分子式 | C19H11NO5S2 |
存储 | Shipping with blue ice. |
评论内容