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TargetMol | Compound Library

抗乳腺癌化合物库现货

Anti-Breast Cancer Compound Library

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产品编号 L2191

乳腺癌是乳腺恶性肿瘤,是全球女性发病率较高的癌症,约占女性癌症患者的20%,也是100多个国家癌症死亡的主要原因。近年来全球乳腺癌发病率一直呈上升趋势。 乳腺癌根据病理分型可分为非浸润性癌,早期浸润性癌,浸润性癌。根据分子分型可分为雌激素受体阳性乳腺癌(ER+PR+HER2-),HER2阳性乳腺癌(ER-PR-HER2+),三阴性乳腺癌(ER-PR-HER2-)。不同类型的乳腺癌,从治疗方法到预后都是非常不同,需要针对已经明确的致癌位点,探索相关靶点来设计相应的药物。 TargetMol 抗乳腺癌库收集了2440 种与乳腺癌相关的化合物,包含了已经报道的有乳腺癌治疗作用的化合物,以及相关的靶点通路(HER-2, VEGF, EGFR, PARP, CDK4/6, HSP, PD-1, SET7/9, BRCA 等),是乳腺癌药物研发的良好工具。

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。

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产品编号 L2191

抗乳腺癌化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 2440种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究;
  • 靶点包含HER-2, VEGF, EGFR, PARP, CDK4/6, HSP, PD-1, SET7/9, BRCA等;
  • 部分化合物已上市或已进入临床期;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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Library Customization | TargetMol 化合物库组成

Apoptosis
CDK
Autophagy
PI3K
EGFR
VEGFR
mTOR
HDAC
COX
PPAR
GSK-3
NF-κB
FGFR
PARP
PDGFR
Akt
HSP
Reactive Oxygen Species
TGF-beta/Smad
AMPK
c-Kit
FLT
Src
DNA-PK
Estrogen/progestogen Receptor
IκB/IKK
HER
Estrogen Receptor/ERR
S6 Kinase
ATM/ATR
Progesterone Receptor
RIP kinase
Aurora Kinase
ALK
c-Met/HGFR
Wnt/beta-catenin
DNA/RNA Synthesis
Ferroptosis
ERK
Bcr-Abl
PD-1/PD-L1
PDK
c-RET
Raf
Endogenous Metabolite
PKC
Gamma-secretase
Antibacterial
Microtubule Associated
JAK
IRAK
PI4K
IGF-1R
Mitophagy
PKA
Chk
Potassium Channel
NOD
Parasite
MAPK
TAM Receptor
Antibiotic
Dehydrogenase
Calcium Channel
Epigenetic Reader Domain
Casein Kinase
STAT
MEK
IL Receptor
c-Fms
TNF
HIV Protease
Phosphatase
Tyrosine Kinases
Topoisomerase
Trk receptor
P450
FAK
NOD-like Receptor (NLR)
SIK
Prostaglandin Receptor
Aromatase
PROTACs
Antioxidant
JNK
TRP/TRPV Channel
ROCK
Drug Metabolite
BTK
Interleukin
Sirtuin
Ras
p53
ADC Cytotoxin
p38 MAPK
DYRK
Histone Demethylase
Nucleoside Antimetabolite/Analog
PDE
Mitochondrial Metabolism
ROS
Androgen Receptor
MELK
Influenza Virus
Beta Amyloid
PLK
Proteasome
Carbonic Anhydrase
Histone Methyltransferase
HCV Protease
Antifungal
NADPH
Virus Protease
Pim
Serine/threonin kinase
GPR
SGK
Syk
Tyrosinase
Tie-2
Rho
Serine Protease
Caspase
Adrenergic Receptor
Glucocorticoid Receptor
CSF-1R
E1/E2/E3 Enzyme
BCL
Fatty Acid Synthase
HSV
MMP
Lipoxygenase
Antiviral
TLR
Ephrin Receptor
Sodium Channel
DHFR
Adenosine Receptor
Histamine Receptor
GTPase
PYK2
Aryl Hydrocarbon Receptor
MAO
IRE1
DNA Alkylation
CaMK
DUB
Wee1
PGE Synthase
Survivin
SARS-CoV
LRRK2
Nrf2
HIF
MLK
Kinesin
Chloride channel
YAP
DNA Alkylator/Crosslinker
LTR
IFNAR
PERK
RAAS
Glutathione Peroxidase
TOPK
c-Myc
ABC
GNRH Receptor
Hck
Antifolate
Cysteine Protease
Leukotriene Receptor
Glutaminase
CXCR
PTEN
GluR
BCRP
P-gp
STING
Free radical scavengers
transporter
PAI-1
GPX
Phospholipase
GABA Receptor
5-HT Receptor
Cannabinoid Receptor
Gap Junction Protein
Discoidin Domain Receptor (DDR)
cholecystokinin
HIF/HIF Prolyl-Hydroxylase
NO Synthase
S1P Receptor
Mdm2
ATPase
NOS
Transferase
ROR
Dopamine Receptor
NUDIX hydrolase
Integrin
MyD88
LPL Receptor
BACE
RAR/RXR 
MRP
HBV
cell cycle arrest
Glucokinase
Immunology/Inflammation related
IAP
Myosin
FLAP
Haspin Kinase
LDL
AAK1 (AP2 associated kinase 1)
Antifection
Opioid Receptor
PROTAC Linker
APC
Hedgehog/Smoothened
FAAH
CCR
Endothelin Receptor
Somatostatin
Epoxide Hydrolase
KSP
cAMP
DNA
Indoleamine 2,3-Dioxygenase (IDO)
SGLT
ATP Citrate Lyase
OXPHOS
Beta-Secretase
MNK
Acyltransferase
Histone Acetyltransferase
Decarboxylase
cGAS
HuR
RSV
GST
Reverse Transcriptase
Retinoid Receptor
Ligand for E3 Ligase
CRISPR/Cas9
Adenosine deaminase
AChR
DAPK
Thrombin
Protease-activated Receptor
ROS Kinase
AhR

Keywords