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VEGFD Protein, Rat, Recombinant (hFc)

产品编号 TMPY-03200

VEGFD Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.6 kDa and the accession number is O35251.

VEGFD Protein, Rat, Recombinant (hFc)

VEGFD Protein, Rat, Recombinant (hFc)

产品编号 TMPY-03200
VEGFD Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.6 kDa and the accession number is O35251.
规格价格库存数量
50 μg¥ 2,9405日内发货
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产品信息

生物活性
Measured by its binding ability in a functional ELISA. Immobilized recombinant Rat VEGF-Dprotein at 10 µg/mL (100 µl/well) can bind biotinylated mouse VEGFR3-Fc with a linear range of 31.25-2000 ng/mL.
产品描述
VEGFD Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.6 kDa and the accession number is O35251.
种属
Rat
表达系统
HEK293 Cells
标签N-hFc
蛋白编号O35251
别名
c-fos induced growth factor (vascular endothelial growth factor D)
蛋白构建
A DNA sequence encoding the rat FIGF (NP_113949.1)(Phe94-Arg210) was expressed, fused with the Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu
蛋白纯度
> 85 % as determined by SDS-PAGE
分子量41.6 kDa (predicted); 52 kDa (reducing conditions)
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice.
研究背景
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.

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