PODXL Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is O00592.

Human

HEK293 Cells

PODXL1,PDX,PCLP-1,PCLP1,PCLP,PC,Gp200,gp135

A DNA sequence encoding the Human PODXL (O00592) (Ser23-Pro461) was expressed with the Fc region of human IgG1 at the C-terminus.

≥ 90% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.

Please refer to the lot-specific COA.

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational epitopes responsible for various pluripotent surface markers including TRA-1-60, TRA-1-81, GCTM2, GP200, and mAb84.Podocalyxin-like 1 (PODXL) was reported to be closely associated with the development of various cancers.KLF4/PODXL signaling pathway assumes an irreplaceable role in tumorigenesis, invasion and metastasis of human GC and PODXL serves as an independent prognostic indicator for GC patients. PODXL may be a novel, non-invasive diagnostic biomarker for the detection of pancreatic cancer.