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EMMPRIN/CD147 Protein, Human, Recombinant (hFc)

产品编号 TMPY-00684

EMMPRIN/CD147 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47 kDa and the accession number is P35613-2.

EMMPRIN/CD147 Protein, Human, Recombinant (hFc)

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产品编号 TMPY-00684

EMMPRIN/CD147 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47 kDa and the accession number is P35613-2.

规格	价格	库存
5 μg	¥ 428	6-8日内发货
10 μg	¥ 683	6-8日内发货
20 μg	¥ 1,130	5日内发货
50 μg	¥ 2,270	5日内发货
100 μg	¥ 4,430	5日内发货
200 μg	¥ 6,730	5日内发货
500 μg	¥ 13,800	5日内发货
1 mg	¥ 28,800	5日内发货

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产品信息

生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	EMMPRIN/CD147 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47 kDa and the accession number is P35613-2.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	P35613-2
别名	TCSF,OK,M6,EMMPRIN,CD147,basigin (Ok blood group),Basigin,5F7
蛋白构建	Ala22-His205
蛋白纯度	> 95% as determined by SDS-PAGE.
分子量	47 kDa (predicted); 55-70 kDa (reducing condition, due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.