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- 3404个临床期化合物集合，可用于高通量筛选和高内涵筛选；
- 所有化合物均已被批准进入临床期，按临床一期、二期、三期等进行分类；
- 是老药新用和细胞诱导的有效工具
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- 结构多样，药效显著，可渗透细胞；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
临床期小分子药物库
Clinical Compound Library
很棒临床期小分子药物库汇集了3404 个已经进入临床实验的化合物，这些化合物经过大量的临床前研究实验，具有活性高、毒性低和机制明确的特点。我们随货信息中每个化合物都包含了其作用靶点、临床期、适应症等信息，涉及癌症、炎症、感染、神经病、心血管病和消化系统疾病等多种热门病症，以及JAK、EGFR、mTOR、CDK、HDAC、AKt、PARP 等众多成药靶点，适用于药物筛选的同时，也是细胞诱导分化的有力工具。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
Excel
SDF
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临床期小分子药物库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
SCI 文献
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化合物库组成
Autophagy
Apoptosis
Antibacterial
Antibiotic
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
DNA/RNA Synthesis
HIV Protease
AChR
Dopamine Receptor
COX
Histamine Receptor
VEGFR
Parasite
Sodium Channel
Calcium Channel
EGFR
PI3K
Antifungal
Potassium Channel
PDE
Topoisomerase
FLT
HCV Protease
CDK
Cytochromes P450
PDGFR
Dehydrogenase
JAK
Microtubule Associated
Reactive Oxygen Species
SARS-CoV
PPAR
FGFR
c-Kit
Glucocorticoid Receptor
mTOR
Ferroptosis
HDAC
Influenza Virus
c-Met/HGFR
Src
Estrogen/progestogen Receptor
GABA Receptor
RAAS
HBV
NF-κB
Mitophagy
Prostaglandin Receptor
Reverse Transcriptase
Nucleoside Antimetabolite/Analog
GPR
Adenosine Receptor
Tyrosine Kinases
Raf
Bcr-Abl
Proteasome
Androgen Receptor
Serotonin Transporter
iGluR
Epigenetic Reader Domain
Aurora Kinase
Akt
Phosphatase
Virus Protease
TRP/TRPV Channel
ROS
HSV
HER
Transferase
p38 MAPK
Progesterone Receptor
Estrogen Receptor/ERR
PARP
GluR
Norepinephrine
Opioid Receptor
ALK
Beta Amyloid
MEK
NMDAR
IL Receptor
HSP
c-RET
TNF
HIF/HIF Prolyl-Hydroxylase
ATPase
DPP-4
P-gp
Trk receptor
Carbonic Anhydrase
Antioxidant
Antifection
Cholinesterase (ChE)
Antiviral
Histone Methyltransferase
GSK-3
ERK
CXCR
c-Fms
ribosome
Thrombin
DNA Alkylator/Crosslinker
PKC
Gamma-secretase
Mitochondrial Metabolism
Endothelin Receptor
Interleukin
TLR
Retinoid Receptor
Proton pump
MAO
CCR
MMP
Chk
Bcl-2 Family
Phospholipase
S1P Receptor
Thyroid hormone receptor(THR)
DNA-PK
LPL Receptor
E1/E2/E3 Enzyme
SGLT
STAT
AMPK
HIF
Syk
CFTR
p53
NO Synthase
Caspase
Guanylate cyclase
TAM Receptor
Integrin
NADPH
Wnt/beta-catenin
Antifolate
CSF-1R
DNA Alkylation
Hedgehog/Smoothened
IGF-1R
Nrf2
Neurokinin receptor
FAK
Mdm2
CETP
Glutathione Peroxidase
MRP
PKA
P2X Receptor
Lipoxygenase
TGF-beta/Smad
Hydroxylase
PLK
Cannabinoid Receptor
Monoamine Oxidase
BTK
P2Y Receptor
Reductase
GNRH Receptor
ROCK
IAP
Drug Metabolite
Vasopressin Receptor
Indoleamine 2,3-Dioxygenase (IDO)
RSV
ATM/ATR
S6 Kinase
HMG-CoA Reductase
ROS Kinase
ADC Cytotoxin
DHFR
Histone Demethylase
JNK
Serine Protease
FXR
Aryl Hydrocarbon Receptor
RIP kinase
Glucosidase
Smo
OX Receptor
Xanthine Oxidase
DNA
Beta-Secretase
Aminopeptidase
Sirtuin
Casein Kinase
Sigma receptor
Kinesin
ROR
Amino Acids and Derivatives
BACE
Pim
Leukotriene Receptor
Glucokinase
Glucagon Receptor
Isocitrate Dehydrogenase (IDH)
PAK
Bradykinin Receptor
IκB/IKK
DNA Methyltransferase
IRAK
AhR
Tie-2
Factor Xa
IDO
DNA gyrase
Fatty Acid Synthase
Acyltransferase
Ephrin Receptor
Ligand for E3 Ligase
Complement System
Chloride channel
NOS
DprE1
YAP
LTR
IFNAR
Melatonin Receptor
Cholecystokinin Receptor
Liver X Receptor
MT Receptor
Monoamine Transporter
Molecular Glues
Neuropeptide Y Receptor
FAAH
KSP
CaMK
Wee1
PGE Synthase
OAT
Decarboxylase
CRFR
Neprilysin
Acetyl-CoA Carboxylase
Melanocortin Receptor
GHSR
CGRP Receptor
Gap Junction Protein
NADPH-oxidase
CRM1
Arginase
Cell wall
PERK
CaSR
Rho
Cysteine Protease
NAMPT
PYK2
Myosin
Annexin A
ABC Transporter
GlyT
Somatostatin
DUB
Telomerase
MAPK
STING
Free radical scavengers
GPCR19
LPA Receptor
PDK
Adenosine Deaminase
Ras
Tyrosinase
Protease-activated Receptor
NOD-like Receptor (NLR)
Imidazoline Receptor
PD-1/PD-L1
Kras
Taste receptor
PROTACs
GSNOR
NEDD8
Ligands for Target Protein for PROTAC
VDA
Galectin
Serine/threonin kinase
IRE1
UGT
LDL
Na-K-Cl cotransporter
Hexokinase
Integrase
HCN Channel
Stearoyl-CoA Desaturase (SCD)
Epoxide Hydrolase
ATP Citrate Lyase
BCRP
Porcupine
CD73
transporter
PAI-1
GST
Oxytocin Receptor
Discoidin Domain Receptor (DDR)
p97
MLK
Advanced Glycation End Products
Adenylyl Cyclase
MicroRNA
Monocarboxylate transporter
NPC1L1
Hydrogenase
RAR/RXR
MALT
Arrestin
DYRK
Lipase
GTPase
c-Myc
N-Acetylglucosaminyltransferase
AAK1
VDAC
Hck
Glutaminase
Stemness kinase
FLAP
PAFR
Fas/FasL
GRK
Phosphorylase
Anion Exchanger
PROTAC Linker
Thioredoxin
ACK1
Lipid
PSMA
Survivin
MNK
Histone Acetyltransferase
GluCls
ASK
Pyroptosis
MELK
Methionine Adenosyltransferase (MAT)
Hippo pathway
Aromatase
PI4K
KLF
CRISPR/Cas9
Aquaporin
RXFP receptor
SGK
Anti-infection
BMI-1
NOD
PKM
Vitamin
Drug-Linker Conjugates for ADC
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