ALPK1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 3,120 | 20日内发货 | ||
100 μg | ¥ 8,760 | 20日内发货 | ||
1 mg | ¥ 17,500 | 20日内发货 |
产品描述 | ALPK1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. |
种属 | Human |
表达系统 | Baculovirus Insect Cells |
标签 | N-10xHis, C-Myc |
蛋白编号 | Q96QP1 |
别名 | KIAA1527, Lymphocyte alpha-protein kinase, Alpha-protein kinase 1, Chromosome 4 kinase, LAK |
氨基酸序列 | KYSKKSELWTAQETIVYLGDYLTVKKKGRQRNAFWVHHLHQEEILGRYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQNIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTTNFGKRGIFYFFNNQHVECNEICHRLSLTRP |
蛋白构建 | 1017-1237 aa |
蛋白纯度 | > 85% as determined by SDS-PAGE. |
分子量 | 29.9 kDa (predicted) |
缓冲液 | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
复溶方法 | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Serine/threonine-protein kinase that detects bacterial pathogen-associated molecular pattern metabolites (PAMPs) and initiates an innate immune response, a critical step for pathogen elimination and engagement of adaptive immunity. Specifically recognizes and binds ADP-D-glycero-beta-D-manno-heptose (ADP-Heptose), a potent PAMP present in all Gram-negative and some Gram-positive bacteria. ADP-Heptose-binding stimulates its kinase activity to phosphorylate and activate TIFA, triggering proinflammatory NF-kappa-B signaling. May be involved in monosodium urate monohydrate (MSU)-induced inflammation by mediating phosphorylation of unconventional myosin MYO9A. May also play a role in apical protein transport by mediating phosphorylation of unconventional myosin MYO1A. May play a role in ciliogenesis. |
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ALPK1 Protein, Human, Recombinant (His & Myc) KIAA1527 Lymphocyte alpha-protein kinase Alpha-protein kinase 1 Chromosome 4 kinase LAK recombinant recombinant-proteins proteins protein