IL-13RA1 Protein, Mouse, Recombinant (His)

产品编号 TMPY-01170

IL-13RA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is O09030.

IL-13RA1 Protein, Mouse, Recombinant (His)

产品编号 TMPY-01170

IL-13RA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is O09030.

规格	价格	库存	数量
50 μg	¥ 780	现货
100 μg	¥ 1,430	5日内发货

大包装 & 定制

加入购物车

实验操作小课堂

选择批次

资源下载

COA 重组蛋白用户指南

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

产品信息

生物活性	1.Measured by its binding ability in a functional ELISA. 2. Immobilized mouse IL13RA1-His at 10μg/mL (100μL/well) can bind human Fc-IL13, the EC50 of human Fc-IL13 is 0.5-1.5 μg/mL.
产品描述	IL-13RA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is O09030.
种属	Mouse
表达系统	HEK293 Cells
标签	C-His
蛋白编号	O09030
别名	NR4,interleukin 13 receptor, α1,interleukin 13 receptor, alpha 1,Il13ra,IL-13r[a],CD213a1,AI882074
蛋白构建	A DNA sequence encoding the extracellular domain (Met 1-Thr 340) of mouse IL13Rα1 (NP_598751.3) precursor was fused with the a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 26
蛋白纯度	> 98 % as determined by SDS-PAGE
分子量	37.6 kDa (predicted); 50-55 kDa (reducing condition, due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.