IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)

产品编号 TMPJ-00284

Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 61-75 KDa and the accession number is P16872.

IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)

产品编号 TMPJ-00284

规格	价格	库存
10 μg	¥ 740	5日内发货
50 μg	¥ 1,970	5日内发货
500 μg	¥ 12,100	5日内发货
1 mg	¥ 17,400	5日内发货

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产品信息

生物活性	Loaded Human IL-7-His on HIS1K Biosensor, can bind Mouse IL-7RA-Fc with an affinity constant of 5.91 nM as determined in BLI assay. (Regularly tested)
产品描述	Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 61-75 KDa and the accession number is P16872.
种属	Mouse
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	P16872
别名	Interleukin-7 receptor subunit α,Interleukin-7 receptor subunit alpha,IL-7R-α,IL-7R-alpha,IL-7RA,IL-7R subunit α,IL-7R subunit alpha,Il7r,IL-7 receptor subunit α,IL-7 receptor subunit alpha,CD127
氨基酸序列	Glu21-Asp239
蛋白构建	Glu21-Asp239
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	61-75 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 10% Sucrose, 3% Glycine, 100 mM NaCl, 0.1 mM EDTA, 0.05% Tween 80, pH 8.0.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.

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关键词

CD-127 CD 127