抗感染

包含2600种核苷模拟物结构。

1213 种具有抗病毒活性的化合物的特有集合，是筛选新型抗病毒药的有效工具；可用于高通量筛选和高内涵筛选；

390 个抗真菌活性化合物的独特集合，包含作用于真菌相关靶点的化合物和临床中用于真菌类疾病的药物，是相关疾病药物筛选的有效工具。

334 种核苷类化合物，包括核苷酸、核苷酸类似物及衍生物等，适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发；

419 种具有抗寄生虫活性的小分子化合物；

904 种具有抗菌活性的化合物，是抗菌药物研发的有力工具；

692 个具有抗菌活性化合物的独特集合，是医药研究的优良工具库和药物筛选的有效载体；

2938 种具有抗感染活性的化合物的特有集合，包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性；

1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；

There are 5968 compounds in the Antibacterial Library.

ChemDiv’s Antiparasite Library contains 25,376 compounds.

Swiss Prot Protein Targets and PDB X Ray Structure Search: ACE2, PLpro, 3CLP Training Sets ChEMBL 25, PubMed, Current Patent Literature (CAS, Integrity)

Antimycobacterial library in Otava contains 1696 compounds

冠状病毒筛选库包含2019-nCoV主要蛋白酶靶向库、eEF1A靶向库、2019-nCoV木瓜样蛋白酶靶向库、SARS冠状病毒重点库

OTAVAchemicals offers SARS-CoV-2 RNA-dependent RNA Polymerase (RdRp) Targeted Library, which contains 1031 compounds with predicted activity against SARS-CoV-2 RdRp.

Diversity of database: 0,8

Nucleoside Mimetics Library contains 3118 compounds.

Antituberculosic library in Otava contains 1828 compounds

OTAVAchemicals offers an Insecticides-Like Library (2,137 compounds).

We offer SARS-CoV-2 Endoribonuclease (NSP15) Targeted Library, which contains 626 compounds.

Coronavirus Mpro covalent Librarycontains 2640 compounds.Designed for the discovery of new SARS-CoV-2 and pan-Coronavirus antivirals.

ChemDiv 的3CLpro 库包含4,792个化合物。 3CLpro，又称Mpro，是一种新冠蛋白酶，负责将一个长长的肽链切开，切成不同的有功能的蛋白。冠状病毒是单链正义RNA 病毒，具有大型病毒RNA 基因组。通常情况下，β-冠状病毒在基因组转录后产生一个约800 kDa 的多肽。该多肽通过蛋白酶解割生成各种蛋白质。蛋白酶解由PLpro 和3-胱抑肽酶样蛋白酶（3CLpro）介导。冠状病毒的3CLpro 属于胱抑肽酶样蛋白酶，不同的是它们在催化二元组中使用半胱氨酸作为亲核试剂，而不是在催化三元组中使用丝氨酸。3CLpro 在溶液中存在单体-二聚体平衡。每个单体由三个结构域组成：结构域I 和结构域II 包含催化位点和胱抑肽酶样骨架，并通过一个长环连接到第三个C-末端结构域。

抗原生动物筛选库包括8,200多种小分子筛选化合物，这些化合物有望对抗主要的原生动物疾病，如贾第鞭毛虫病、利什曼病、疟疾、滴虫病和锥虫病。

Life Chemicals设计了两个抗结核病筛选库，其中包含超过11,800种针对关键蛋白质靶点的药物样筛选化合物，促进高通量筛选（HTS）在抗结核药物研究中的应用。

We offer SARS-CoV-2 Nonstructural Protein 14 (NSP14) Targeted Library, which contains 1490 compounds. The library has been designed with receptor-based virtual screening using the homology model of SARS-CoV-2 NSP14.

Antibacterial Library in UORSY contains 6104 compounds.

Anti-HIV Screening Libraries contain 16800 compounds.

抗病毒包含20,000种具有潜在抗病毒活性的类药筛选化合物，可用于高通量筛选（HTS）和高内涵筛选（HCS）项目。

ChemDiv 的抗 HBV 病毒库包含11,000个化合物。

Antiviral Library in UORSY contains 4183 compounds.

We offer Viral RNA-dependent RNA Polymerases (RdRPs) Targeted Library, which contains 1259 compounds with predicted activity against viral RdRPs.

We offer SARS-CoV-2 Helicase (NSP13) Targeted Library, which contains 1170 compounds with predicted activity against this vital protein.

More than 15,000 high-quality compounds from ChemBridge's stock of 1.3 million compounds were identified to compose the Coronavirus Library.

核苷类似物库包含320个化合物。

There are 1017 compounds in the library.

ChemDiv presents a brand new library – Opportunistic Pathogens of Immunocompromised Hosts Annotated Library (OPICH library), which consists of over 2,500 compounds.

Combined annotated pool Analyses of: • isosteric & bioisosteric transformations • hot-spots & crucial binding points • scaffold hopping

OTAVAchemicals offers Machine Learning (ML) SARS Targeted Library, which contains 1577 compounds with predicted activity against SARS-CoV-2.

ChemDiv’s Anti-HIV1 Library contains 21,000 compounds.

ChemDiv’s Antifungal Library contains 16,824 compounds.

97 种β-内酰胺类化合物的集合，可以用于高通量和高内涵筛选；

ChemDiv的ACE2库包含3,051个化合物。 ACE2（血管紧张素转化酶2）是RAAS反调节途径的关键组成部分，它调节血压、炎症和纤维化，并对高血压、心血管疾病和慢性肾脏疾病的病理生理学至关重要。ACE2将Ang II转化为Ang-(1-7)，降低血压，减少炎症和纤维化。Ang-(1-7)的主要作用是促进血管舒张、钠和水排泄，减少交感神经系统紧张度，并增加一氧化氮的产生。

ChemDiv’s Antiviral Library contains 87,000 compounds.

Nucleoside-mimetics Pre-Plated Set contains 3661 compounds.