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CXCR3 Protein-VLP, Human, Recombinant (Flag & His-Strep)

产品编号 TMPY-07103

CXCR3 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is P49682.

CXCR3 Protein-VLP, Human, Recombinant (Flag & His-Strep)

CXCR3 Protein-VLP, Human, Recombinant (Flag & His-Strep)

产品编号 TMPY-07103
CXCR3 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is P49682.
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产品信息

生物活性
Immobilized CXCR3 Protein-VLP, Human, Recombinant (Flag & His-Strep) (Cat#TMPY-07103) at 5 μg/mL (100 μL/well) can bind Anti-CXCR3 Monoclonal Antibody, Human IgG1, the EC50 is 6-20 ng/mL.
产品描述
CXCR3 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is P49682.
种属
Human
表达系统
HEK293 Cells
标签N-Flag, C-His-Strep
蛋白编号P49682
蛋白构建
A DNA sequence encoding the Human CXCR3 (P49682) (Met1-Leu368) was expressed, with a Flag tag at the N-terminus, a polyhistidine tag and a strep tag at the C-terminus.
分子量44.55 kDa (predicted)
内毒素< 1.0 EU per μg protein as determined by the LAL method.
缓冲液Supplied as sterile 50 mM Hepes, 150 mM NaCl, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
存储
Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
运输方式It is supplied and shipped as liquid with dry ice.
研究背景
The chemokine receptor CXCR3 plays an important role in T cell recruitment in various immune responses and autoimmune diseases. CXCR3 overexpression in GC is associated with increased DC and TIL infiltration and improved OS, and thus could be further exploited as a biomarker of favorable prognosis and a therapeutic target in GC. CXCR3 is a chemokine receptor expressed on a wide range of leukocytes, and it is involved in leukocyte migration throughout the blood and lymphatics.

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