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BMP-7 Protein, Human, Recombinant
产品编号 TMPJ-01473
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a state of leptin-resistance, thus a protein-like BMP7 which acts through a leptin-independent pathway could give new therapeutic directions.
BMP-7 Protein, Human, Recombinant
产品编号 TMPJ-01473
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a state of leptin-resistance, thus a protein-like BMP7 which acts through a leptin-independent pathway could give new therapeutic directions.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 10 μg | ¥ 1,970 | 期货 | |
| 50 μg | ¥ 7,415 | 期货 | |
| 500 μg | ¥ 37,115 | 期货 |
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产品信息
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 产品描述 | Recombinant Human Bone morphogenetic protein 7 is produced by our Mammalian expression system and the target gene encoding Ser293-His431 is expressed. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | Tag Free |
| 蛋白编号 | P18075 |
| 别名 | Osteogenic protein 1,OP-1,OP1,Eptotermin alfa,Bone morphogenetic protein 7,BMP7 |
| 氨基酸序列 | Ser293-His431 |
| 蛋白构建 | Ser293-His431 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 分子量 | 18-23 KDa (reducing condition) |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 缓冲液 | Supplied as a 0.2 μm filtered solution of 20 mM PB, 100 mM NaCl, 5% Mannitol, 0.05% Tween 80, pH7.5. |
| 存储 | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 6 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a state of leptin-resistance, thus a protein-like BMP7 which acts through a leptin-independent pathway could give new therapeutic directions. |
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