CAY10726

Name: CAY10726
Brand: TargetMol
SKU: T36194
Price: 2120 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T36194Cas号 1611446-66-2

别名 CAY10726

CAY10726 is an arylurea fatty acid. It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane.

CAY10726

还可以

产品编号 T36194 别名 CAY10726Cas号 1611446-66-2

规格	价格	库存
1 mg	¥ 560	35日内发货
5 mg	¥ 2,430	35日内发货
10 mg	¥ 4,250	35日内发货
25 mg	¥ 9,320	35日内发货

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产品介绍

生物活性

产品描述	CAY10726 is an arylurea fatty acid. It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane.
体内活性	In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner.
别名	CAY10726

化学信息

分子量	493
分子式	C₂₄H₃₆ClF₃N₂O₃
CAS No.	1611446-66-2
密度	1.176 g/cm3 (Predicted)

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
溶解度信息	DMSO: 5 mg/mL Ethanol: 12 mg/mL DMF:PBS(pH7.2) (1:2): 0.33 mg/mL DMF: 20 mg/mL