购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
TargetMol | Compound Library

抗癌上市药物库现货

Anti-Cancer Approved Drug Library

Rating icon 很棒
产品编号 L2110

尽管在过去的几十年中癌症的研究和治疗取得了巨大的成功,但癌症仍然是人类面临的巨大挑战,给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征,表现出无限的增殖潜能,维持自身生长信号的持续稳定,逃避应激信号诱导的细胞凋亡,刺激血管生长,为肿瘤提供营养,同时逃避免疫系统防御和诱导局部慢性炎症,发挥其侵袭和转移能力,表现出异常的代谢活动,并通过突变和表观遗传机制显著改变全基因组的稳定性。 根据文献报道和有关公开资料,我们挑选了1779 个具有抗癌活性或潜在抗癌活性的上市药物组成抗癌上市药物库,可用于具体癌症的阳性对照及不同癌症之间相关性研究。如果您对癌症相关适应症感兴趣,还可以关注我们其他三个库:抗癌分子库,癌细胞分化分子库,以及抗癌临床药物库。希望我们在抗癌研究的路上,助您一臂之力!

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。

资源下载
化合物库相关信息
Excel
SDF
联系我们获取更多批次信息

产品编号 L2110

抗癌上市药物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 1779个具有抗癌活性小分子的独特集合,所有化合物都经过了严格的临床前研究和临床试验,由FDA、EMA或NMPA批准上市,可用于高通量、高内涵筛选。
  • 所有化合物都具有已知且良好的生物活性、安全性和生物利用度,这些特性可显着加速药物开发和优化,是进行癌症相关研究和药物重定位有效的筛选工具。
  • 作用靶点涉及PI3K、HDAC、mTOR、CDK、JAK 等癌症相关靶点,涉及的研究领域包括肺癌、乳腺癌、白血病、淋巴瘤等15种癌症;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

使用TargetMol产品
发表顶级期刊文献

引用更多关于TargetMol产品的科学文献吧!

查看更多

Library Customization | TargetMol 化合物库定制

Compound Library | TargetMol
您可以通过点击按钮
定制您专属的化合物!
联系专属定制

Library Customization | TargetMol 化合物库组成

Autophagy
Apoptosis
Adrenergic Receptor
5-HT Receptor
COX
Dopamine Receptor
Histamine Receptor
Antibacterial
Antibiotic
Sodium Channel
Calcium Channel
Potassium Channel
DNA/RNA Synthesis
AChR
Glucocorticoid Receptor
P450
Parasite
VEGFR
c-Kit
HIV Protease
PDGFR
Antifungal
EGFR
Estrogen/progestogen Receptor
PPAR
GABA Receptor
Estrogen Receptor/ERR
Nucleoside Antimetabolite/Analog
SARS-CoV
Prostaglandin Receptor
Endogenous Metabolite
Ferroptosis
Serotonin Transporter
Norepinephrine
Proton pump
Mitophagy
PDE
FLT
Src
Dehydrogenase
Topoisomerase
JAK
RAAS
Bcr-Abl
Androgen Receptor
NF-κB
FGFR
ATPase
DNA Alkylator/Crosslinker
ADC Cytotoxin
c-Met/HGFR
HDAC
Microtubule Associated
Reactive Oxygen Species
HSV
Influenza Virus
HBV
Tyrosine Kinases
iGluR
ALK
Progesterone Receptor
GNRH Receptor
PARP
CDK
Opioid Receptor
SGLT
Antifolate
Raf
c-RET
Carbonic Anhydrase
Virus Protease
PKC
MAO
NMDAR
P-gp
Reverse Transcriptase
Retinoid Receptor
HER
Proteasome
DHFR
HCV Protease
P2Y Receptor
Adenosine Receptor
MRP
TRP/TRPV Channel
BTK
ROS
DNA Alkylation
PI3K
Phosphatase
Drug Metabolite
Antifection
Guanylate cyclase
CaMK
Trk receptor
MEK
TAM Receptor
Thrombin
Monoamine Oxidase
Hedgehog/Smoothened
Kras
Aromatase
AMPK
Phospholipase
TNF
Neurokinin receptor
HMG-CoA Reductase
ROS Kinase
CFTR
Chloride channel
Histone Methyltransferase
ABC
ROCK
ERK
Monoamine Transporter
IL Receptor
Vasopressin Receptor
Endothelin Receptor
MMP
GluR
DNA
mTOR
Interleukin
STAT
DNA Methyltransferase
S1P Receptor
Transferase
LPL Receptor
NADPH
CaSR
Annexin A
Smo
DPP-4
Lipoxygenase
PGE Synthase
Antiviral
TLR
ribosome
GPR
HIF
Sigma receptor
HIF/HIF Prolyl-Hydroxylase
NO Synthase
Antioxidant
Glutathione Peroxidase
Melatonin Receptor
PKA
Serine Protease
Serine/threonin kinase
Cysteine Protease
Leukotriene Receptor
Caspase
P2X Receptor
Na-K-Cl cotransporter
Mitochondrial Metabolism
Molecular Glues
Isocitrate Dehydrogenase (IDH)
BCL
Fatty Acid Synthase
Xanthine Oxidase
IGF-1R
Akt
AChE
HSP
Free radical scavengers
Ligand for E3 Ligase
c-Fms
Melanocortin Receptor
Oxytocin Receptor
Hydroxylase
Adenosine deaminase
Syk
FAK
AhR
NOS
CAT
Integrin
CRM1
p38 MAPK
Ligands for Target Protein for PROTAC
YAP
IFNAR
GSK-3
Wnt/beta-catenin
Rho
FXR
IRE1
Gamma-secretase
MT Receptor
Hexokinase
Somatostatin
Beta-Secretase
MAPK
OAT
Ephrin Receptor
Nrf2
RSV
IκB/IKK
GST
Beta Amyloid
GHSR
CGRP Receptor
Gap Junction Protein
Ras
cholecystokinin
Tyrosinase
Protease-activated Receptor
Thyroid hormone receptor(THR)
NPC1L1
Monocarboxylate transporter
ROR
Amino Acids and Derivatives
LTR
Reductase
Na+/Ca2+ Exchanger
RAR/RXR 
Histone Demethylase
JNK
TOPK
VDA
Hck
Aryl Hydrocarbon Receptor
CSF-1R
Immunology/Inflammation related
Adiponectin receptor
UGT
PAFR
MTH1
LDL
GRK
Glucagon Receptor
DNA gyrase
PROTAC Linker
HCN Channel
PAK
FAAH
CCR
Bradykinin Receptor
CXCR
Chk
ACK
Aurora Kinase
cAMP
Thrombopoietin Receptor
Epigenetic Reader Domain
DUB
TGF-beta/Smad
ATP Citrate Lyase
Aminopeptidase
GPCR19
Decarboxylase
Pyroptosis
Neprilysin
PLK
Complement System
Cannabinoid Receptor
NADPH-oxidase
NOD
S6 Kinase
NOD-like Receptor (NLR)
Imidazoline Receptor
PD-1/PD-L1

Keywords