IL-17RD Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-65 KDa and the accession number is Q8JZL1.

Mouse

HEK293 Cells

Sef,mSef,Interleukin-17 receptor-like protein,Il17rlm,Interleukin-17 receptor D,IL-17 receptor D,Il17rd,IL-17RD

Cys17-Arg299

Cys17-Arg299

Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in zebrafish development, is the only orphan receptor without any known ligand within the IL-17R family. IL-17RD is a transmembrane protein shown to inhibit fibroblast growth factor signaling in developmental and cancer contexts, however its role as a tumor suppressor remains to be fully elucidated. The full-length IL-17 RD isoform is expressed in most adult tissues and during embryonic development.