FDA上市及药典收录分子库

规格
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

产品描述

3158个上市及药典分子集合，可用于高通量筛选和高内涵筛选；
所有化合物得到FDA、EMA、CFDA等权威部门审批或收录在USP、EP，BP、JP、CP等药典文献中；
老药新用、细胞诱导的有效工具；
涵盖多个研究领域：肿瘤、心血管药物、抗炎/免疫、神经系统药物、呼吸系统药物等；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
结构多样，药效显著，可渗透细胞；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

TargetMol的化合物可以高度定制！ 了解更多

包装和存储

干粉或者DMSO溶液置于带二维码的储存管中，或排列于96孔板/384孔板；
蓝冰运输

文件下载

化合物库操作手册 (1.89 MB) TargetMol化合物库目录 (2.39 MB) 获取化合物库Excel和SDF列表文件

客户使用化合物库发表的文献

1. Antiviral Research. 2022: 105417. 2. International Journal of Molecular Medicine. 2023, 51(6): 1-13. 3. Cell Stem Cell. 2022 Apr 29(4) 545–558. 4. Science Bulletin. 2022. 5. Science Translational Medicine. 2022, 14(656): eabn3231. 6. Science Advances. 2023, 9(9): eade3760. 7. Nature. 2020, 582: 289-293. 8. Nature Biotechnology. 2021, 39(11): 1444-1452. 9. Nature Communications. 2022, 13(1): 1-15..

10. Nature Communications. 2023, 14(1): 1020.. 11. Nature Communications. 2023, 14(1): 2756.. 12. Blood. 2021, 137(11): 1478-1490. 13. Nucleic Acids Research. 2021. 14. Nature Communications. 2023, 14(1): 7574. 15. Advanced Science. 2020, 7(16): 2000925. 16. Angewandte Chemie. 2021. 17. Acta Pharmaceutica Sinica B. 2022. 18. Protein & Cell. 2021, 12(11): 877-888. 19. Bone Research. 2023, 11(1): 54. 20. Pharmacology & Therapeutics. (2021): 107930. 21. Nature Communications. 2021, 12(1): 1-12. 22. Journal of Cell Biology. 2022, 221(5): e202112024.

下拉查看更多收起

化合物库组成

Antibacterial (473)

Antibiotic (425)

Autophagy (361)

Endogenous Metabolite (318)

Apoptosis (294)

Adrenergic Receptor (167)

5-HT Receptor (164)

AChR (141)

COX (135)

Parasite (131)

Histamine Receptor (115)

Dopamine Receptor (111)

Antifungal (110)

HIV Protease (91)

Sodium Channel (84)

Calcium Channel (82)

DNA/RNA Synthesis (81)

Potassium Channel (80)

NF-κB (57)

Topoisomerase (54)

Reactive Oxygen Species (52)

Estrogen/progestogen Receptor (52)

Influenza Virus (51)

Glucocorticoid Receptor (51)

P450 (50)

Ferroptosis (47)

PDE (45)

SARS-CoV (45)

RAAS (40)

GABA Receptor (38)

Dehydrogenase (38)

Mitophagy (36)

EGFR (35)

VEGFR (33)

HCV Protease (33)

ribosome (32)

c-Kit (32)

HSV (31)

Serotonin Transporter (30)

PPAR (30)

PDGFR (30)

Microtubule Associated (29)

Nucleoside Antimetabolite/Analog (29)

Estrogen Receptor/ERR (29)

Prostaglandin Receptor (29)

AChE (29)

Reverse Transcriptase (28)

MAO (27)

Virus Protease (27)

Progesterone Receptor (26)

Norepinephrine (24)

HBV (24)

Antioxidant (24)

Proteasome (23)

Antifection (22)

ATPase (22)

iGluR (22)

Androgen Receptor (20)

TNF (20)

FGFR (20)

Carbonic Anhydrase (20)

TRP/TRPV Channel (19)

HDAC (19)

Monoamine Oxidase (19)

Proton pump (19)

JAK (19)

MMP (18)

FLT (18)

Opioid Receptor (17)

Thrombin (17)

Bcr-Abl (16)

Src (16)

PKC (16)

DNA Alkylator/Crosslinker (16)

Transferase (16)

Adenosine Receptor (16)

ROS (16)

IL Receptor (15)

Tyrosine Kinases (15)

Phosphatase (15)

c-Met/HGFR (15)

DPP-4 (15)

Antiviral (15)

GluR (14)

NMDAR (14)

HIF/HIF Prolyl-Hydroxylase (14)

MRP (14)

Drug Metabolite (14)

PI3K (13)

Lipoxygenase (13)

NO Synthase (13)

CDK (13)

ERK (12)

Retinoid Receptor (12)

GNRH Receptor (12)

AMPK (12)

Raf (12)

Tyrosinase (12)

HMG-CoA Reductase (12)

DHFR (12)

Phospholipase (11)

STAT (11)

Beta Amyloid (11)

Antifolate (11)

Thyroid hormone receptor(THR) (11)

PARP (11)

P-gp (11)

ALK (11)

Interleukin (11)

SGLT (11)

Amino Acids and Derivatives (11)

Factor Xa (10)

Nrf2 (10)

Akt (10)

mTOR (10)

Mitochondrial Metabolism (10)

MEK (9)

c-RET (9)

DNA Alkylation (9)

BTK (9)

DNA gyrase (9)

HER (9)

Serine Protease (8)

TLR (8)

P2Y Receptor (8)

CAT (8)

ABC (8)

p38 MAPK (8)

CaMK (8)

Chloride channel (8)

CFTR (7)

TAM Receptor (7)

Neurokinin receptor (7)

NADPH (7)

BCL (7)

DNA Methyltransferase (7)

S1P Receptor (7)

PKA (7)

Cysteine Protease (7)

Monoamine Transporter (7)

Reductase (7)

Trk receptor (7)

GPR (7)

Glutathione Peroxidase (6)

ROCK (6)

Caspase (6)

TGF-beta/Smad (6)

LPL Receptor (6)

Aromatase (6)

Wnt/beta-catenin (6)

Hedgehog/Smoothened (6)

Endothelin Receptor (6)

IκB/IKK (6)

P2X Receptor (6)

Histone Methyltransferase (6)

HSP (6)

Hydroxylase (5)

Lipid (5)

Guanylate cyclase (5)

Fatty Acid Synthase (5)

Ras (5)

PGE Synthase (5)

Integrin (5)

FAK (5)

Cannabinoid Receptor (5)

Cell wall (5)

Serine/threonin kinase (5)

GSK-3 (5)

ROS Kinase (5)

HIF (5)

Anti-infection (5)

DNA (5)

FXR (5)

Vasopressin Receptor (5)

Annexin A (5)

Xanthine Oxidase (5)

Decarboxylase (4)

GPCR19 (4)

CaSR (4)

Sigma receptor (4)

MT Receptor (4)

NOD-like Receptor (NLR) (4)

Gamma-secretase (4)

AhR (4)

Aryl Hydrocarbon Receptor (4)

UGT (4)

NOD (4)

Smo (4)

Oxytocin Receptor (4)

Neprilysin (4)

Melatonin Receptor (4)

NOS (4)

Histone Demethylase (4)

Leukotriene Receptor (3)

PKM (3)

IGF-1R (3)

c-Fms (3)

Molecular Glues (3)

Isocitrate Dehydrogenase (IDH) (3)

Aurora Kinase (3)

CCR (3)

p53 (3)

Na-K-Cl cotransporter (3)

Adenosine deaminase (3)

GluCls (3)

LDL (3)

Free radical scavengers (3)

Gap Junction Protein (3)

cholecystokinin (3)

PAK (3)

Melanocortin Receptor (3)

Aminopeptidase (3)

Arginase (3)

Glucosidase (3)

Hexokinase (3)

Ligand for E3 Ligase (3)

GST (3)

Imidazoline Receptor (3)

CXCR (3)

Sirtuin (3)

JNK (3)

CETP (3)

Syk (3)

CRM1 (2)

Monocarboxylate transporter (2)

GlyT (2)

Integrase (2)

ROR (2)

RSV (2)

Protease-activated Receptor (2)

PDK (2)

Adiponectin receptor (2)

MAPK (2)

PLK (2)

IRE1 (2)

LTR (2)

Somatostatin (2)

CGRP Receptor (2)

IFNAR (2)

DUB (2)

Ephrin Receptor (2)

TOPK (2)

Phosphorylase (2)

Epigenetic Reader Domain (2)

S6 Kinase (2)

Acyltransferase (2)

OAT (2)

DYRK (2)

Telomerase (2)

Beta-Secretase (2)

Complement System (2)

Indoleamine 2,3-Dioxygenase (IDO) (2)

YAP (2)

Immunology/Inflammation related (2)

Ligands for Target Protein for PROTAC (2)

Thrombopoietin Receptor (2)

Rho (2)

Platelet aggregation (2)

Glutathione reductase (2)

transporter (1)

GRK (1)

PAD (1)

Chk (1)

GHSR (1)

Angiotensin-converting Enzyme (ACE) (1)

Hck (1)

RAR/RXR (1)

Bradykinin Receptor (1)

Aquaporin (1)

PROTAC Linker (1)

IAP (1)

Casein Kinase (1)

IRAK (1)

Taste receptor (1)

ATP Citrate Lyase (1)

RANKL/RANK (1)

VDA (1)

NPC1L1 (1)

Epoxide Hydrolase (1)

NADPH-oxidase (1)

Glucagon Receptor (1)

advanced glycation end products (1)

Na+/Ca2+ Exchanger (1)

Pyroptosis (1)

FAAH (1)

MTH1 (1)

Anion Exchanger (1)

Histone Acetyltransferase (1)

Dynamin (1)

cAMP (1)

Mdm2 (1)

PAFR (1)

Hydrogenase (1)

CRISPR/Cas9 (1)

N-Acetylglucosaminyltransferase (1)

CSF-1R (1)

DNA-PK (1)

STING (1)

OX Receptor (1)

ACK (1)

Glucokinase (1)

PD-1/PD-L1 (1)

Lipase (1)

Myosin (1)

gp120/CD4 (1)

BACE (1)

Liver X Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty