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Targets Recommended: PI3K

8989

抑制剂 & 化合物

185

天然产物

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化合物库

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TargetMol 试剂盒

46

重组蛋白

90

同位素标记化合物

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Cat. No. Product Name
L2010 高选择性抑制剂库

575 compounds
575种具有高选择性的抑制剂集合
L9410 共价抑制剂库

1920 compounds
1920 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发;
L7200 钙通道分子库

140 compounds
140 种钙通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L7400 钠通道分子库

118 compounds
118 种钠通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L7300 钾通道分子库

152 compounds
152 种钾通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L5900 血脑屏障通透化合物库

509 compounds
509 个 CNS-Penetrant 生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2520 糖代谢化合物库

702 compounds
702 种糖代谢相关的化合物,可用于高通量和高内涵筛选;

化合物库

高选择性抑制剂库
Cat.No: L2010
Compounds: 575
共价抑制剂库
Cat.No: L9410
Compounds: 1920
钙通道分子库
Cat.No: L7200
Compounds: 140
钠通道分子库
Cat.No: L7400
Compounds: 118
钾通道分子库
Cat.No: L7300
Compounds: 152
血脑屏障通透化合物库
Cat.No: L5900
Compounds: 509
糖代谢化合物库
Cat.No: L2520
Compounds: 702
Cat. No. Product Name Form Specificity Of Inhibition
C0048 Deacetylase Inhibitor Cocktail (100× in 70% DMSO)

去乙酰化酶抑制剂 Cocktail(100× in 70% DMSO)

Solution (100× in 70% DMSO) Class I/II/III HDAC

TargetMol 试剂盒

去乙酰化酶抑制剂 Cocktail(100× in 70% DMSO)
Cat.No: C0048
Cat. No. Product Name Target Signaling Pathways
T5831 Selective PI3Kδ Inhibitor 1

PI3K PI3K/Akt/mTOR signaling
Selective PI3Kδ Inhibitor 1 是一种 PI3Kδ 抑制剂 (IC50 = 0.9 nM)。
T79184 FKBP51F67V-selective antagonist Ligand2

FKBP Apoptosis; Autophagy; Immunology/Inflammation
FKBP51F67V-selective antagonist Ligand2(示例3-3)是针对杏仁核中由FKBP51 F67V过表达引起的焦虑表型的有效逆转剂。本物质特异性地结合到FKBP51 F67V,与野生型FKBP51及FKBP52无亲和力。
T80930 TRPV2-selective blocker 1

Others Others
TRPV2-selective blocker 1 (compound IV2-1) 为选择性TRPV2通道阻断剂,具有6.3 μM IC50,不对TRPV1、TRPV3和TRPV4通道产生影响。该化合物能够抑制巨噬细胞中TRPV2介导的Ca2+流入,进而抑制其吞噬功能。
T16129 MPI_5a

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
MPI_5a 是高效的 HDAC6选择性抑制剂,IC50=36 nM,对其他 HDAC 酶几乎无抑制作用。MPI_5a 抑制细胞内酰基微管蛋白积累, IC50为 210 nM。
T19777 ODQ

Apoptosis; Others; Guanylate cyclase Apoptosis; GPCR/G Protein; Others
ODQ 是一种选择性可溶性的鸟苷酰环化酶抑制剂,可增强顺铂促人间皮瘤细胞凋亡的作用。
T19891 Metolachlor

Others Others
Metolachlor 是出苗前的选择性的,氯乙酰苯胺除草剂,由四种立体异构体组成的手性除草剂。它可用于控制玉米和其他农作物中的各种一年生草和阔叶杂草。
T8513 Spastazoline

Others Others
Spastazoline 是spastin(一种微管切断AAA 蛋白) 的选择性抑制剂,对人 spastin 的IC50值为 99 nM。它不能影响重组人 VPS4 的 ATPase 活性。
T8485 THIQ

Melanocortin Receptor GPCR/G Protein; Neuroscience
THIQ 是一种选择性黑皮质素 4 受体 (MC4R) 激动剂,对 hMC4R 和 rMC4R 的 IC50 分别为 1.2 和 0.6 nM。
T8580 Bupranolol

Adrenergic Receptor GPCR/G Protein; Neuroscience
Bupranolol 是竞争性的、口服活性的、非选择性的β-adrenoceptor 拮抗剂,无固有的拟交感神经活性。
T9570 Enpatoran

TLR Immunology/Inflammation
Enpatoran (M5049) 是一种口服有效的TLR7/8选择性抑制剂,在HEK293 细胞中,IC50s 分别为 11.1 nM 和 24.1 nM。Enpatoran 可以阻断分子合成配体和天然内源性 RNA 配体。Enpatoran 在体内具有良好的药代动力学特性。Enpatoran 在先天性和适应性自身免疫阻断方面有研究的价值。
T2430 HPOB

Apoptosis; HDAC Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
HPOB 是一种高选择性HDAC6抑制剂,IC50为 56 nM,其选择性是其他 HDAC 的 30 倍以上。它提高 DNA 损伤抗癌药物在转化细胞中的有效性。
T22518 5-BDBD

P2X Receptor Membrane transporter/Ion channel; Neuroscience
5-BDBD 是选择性P2X4受体拮抗剂,抑制 rP2X4R 介导的电流,IC50为0.75μM。它可完全阻断硝酸甘油诱导的基础性和急性痛觉过敏。
T16745 Rhosin hydrochloride

Apoptosis; Rho; Ras Apoptosis; Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
Rhosin hydrochloride 是一种特异性 RhoA 亚家族Rho GTPases 抑制剂,抑制 RhoA-GEF 相互作用。它通过增强 D1 中棘神经元的可塑性和降低过度兴奋性来促进应激恢复,可诱导细胞凋亡。
T2293 SGX-523

Raf; p38 MAPK; c-Met/HGFR; Bcr-Abl Angiogenesis; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors
SGX523 是选择性的和 ATP 竞争性的MET 抑制剂 (IC50:4 nM)。它对 MET 的选择性其它他蛋白激酶高 1000 倍。它具有抗肿瘤特性。
T9925 Ofatumumab

Others Others
Ofatumumab 是一种人源化靶向抗 CD20单克隆抗体。它作用于表达 CD20 的 B 淋巴细胞,能够诱导产生抗体依赖性细胞介导的细胞毒性和补体依赖性细胞毒性的作用。
T3624 A-366

A 366,A366

Epigenetic Reader Domain; Histone Methyltransferase Chromatin/Epigenetic
A-366 是一种高选择性的肽竞争性组蛋白甲基转移酶 G9a 抑制剂,对 G9a 和 GLP 的 IC50分别为 3.3 和 38 nM。它比其他 21 种甲基转移酶具有 1000 倍以上的选择性。它是 Spindlin1-H3K4me3相互作用的抑制剂,IC50为182.6 nM。它对人 H3R 表现出很高的亲和力,Ki 值为 17 nM,在组胺能和多巴胺能受体家族的亚群间表现出亚型选择性。
T15729 LDN-91946

DUB Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
LDN-91946 是一种有效且特异性的泛素 C-末端水解酶-L1 (UCH-L1) 抑制剂(Ki = 2.8 μM)。
T8535 GAK inhibitor 49

Serine/threonin kinase Cell Cycle/Checkpoint; Metabolism
GAK inhibitor 49 是 ATP 竞争性的细胞周期蛋白 G 相关激酶选择性抑制剂,Ki=0.54 nM,细胞 IC50=56 nM。它也具有与 RIPK2 结合的能力。
T9118 KEA1-97

Apoptosis; Others; Caspase Apoptosis; Others; Proteases/Proteasome
KEA1-97 是一种选择性硫氧还蛋白-半胱天冬酶 3相互作用干扰剂,IC50为10 μM。它在不影响硫氧还蛋白活性的情况下, 破坏硫氧还蛋白与 caspase 3 的相互作用,激活半胱天冬酶,诱导细胞凋亡。
T2164 Wiskostatin

Others Others
Wiskostatin 是神经元 Wiskott-Aldrich 综合征蛋白介导的肌动蛋白聚合的选择性抑制剂,能够不可逆的使细胞 ATP 水平快速下降。
T9882 RUVBL1/2 ATPase-IN-1

Others Others
RUVBL1/2 ATPase-IN-1 是一种有效的 RUVBL1/2 ATPase 抑制剂,IC50 值分别为 6.0 和 7.7 μM。 RUVBL1/2 ATPase-IN-1 可用于癌症疾病的研究。
T9452 PW0787

GPR Endocrinology/Hormones; GPCR/G Protein
PW0787 是一种可透过血脑屏障的,口服具有活性的GPR52选择性激动剂 (EC50=135 nM)。它能够抑制精神刺激行为。
T7538 Tetraethylammonium chloride

Potassium Channel Membrane transporter/Ion channel
Tetraethylammonium chloride 是非选择性钾通道阻滞剂。它是有机阳离子转运蛋白的良好底物,并具有抗肿瘤特性。
T22341 GSK-114

Others Others
GSK 114 是口服有活性的、高选择性的TNNI3K 抑制剂 (IC50= 25 nM)。其中TNNI3K (又称 CARK) 是酪氨酸样激酶家族的成员,选择性在心脏组织中表达。它对 TNNI3K 的选择性是 B-Raf 激酶的 40 倍 (IC50= 1 µM)。
T7659 Bisindolylmaleimide IV

Others; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Others
Bisindolylmaleimide IV 是一种蛋白激酶 C 细胞渗透抑制剂,其 IC50范围为 0.1-0.55 μM。它也抑制 PKA,IC50范围为3.1-11.8 μM。在细胞培养中,它有效抑制人巨细胞病毒(HCMV)复制,IC50为 0.2 μM。
T11689 ITI-214

ITI214

PDE Metabolism
ITI-214 是一种中枢神经系统活性抑制剂,具有口服生物活性的PDE1抑制剂 (Kiof 58 pM),对其他 PDE 家族成员和一系列酶、受体、转运体和离子通道具有良好的选择性,在各种运动和认知功能的动物模型中显示出有效性。
T7149 S29434

NADPH; Autophagy Autophagy; Metabolism
S29434 是一种竞争性、选择性和可透过细胞膜的醌还原酶 2 抑制剂,对人 QR2 的 IC50值为 5-16 nM。它可诱导自噬,抑制 QR2 介导的 ROS 的产生。
T22748 DQP 1105

NMDAR Neuroscience
DQP 1105 是一种高效非竞争性NMDA 受体拮抗剂。DQP-1105 抑制含有 GluN2C (IC50:7.0 Μm) 和 GluN2D (IC50:2.7 Μm) 的受体 。 IC50值至少比重组 GluN2B-、GluN2A-、GluA1- 或 GluK2 受体低 50 倍。
T8418 DCLK1-IN-1

Others Others
DCLK1-IN-1 是选择性的、体内相容的双皮质素样激酶1DCLK1激酶结构域化学探针。它抑制 DCLK1 和 DCLK2 激酶。它具有低毒性,可以研究 DCLK1 的生物学特性,确定其在肿瘤中的作用,如 DCLK1+胰腺导管腺癌。
T7414 ARS-853

Apoptosis; Raf; Ras Apoptosis; GPCR/G Protein; MAPK
ARS-853 是一种选择性共价KRAS G12C 抑制剂,IC50为 2.5 μM。它通过与 GDP 结合的癌蛋白结合并阻止激活来抑制突变 KRAS 驱动的信号传导。
T11014 DFP00173

Aquaporin Membrane transporter/Ion channel
DFP00173 是一种aquaporin-3 (AQP3)的选择性抑制剂。它对 AQP3 的选择性高于同源 AQP 亚型 AQP7 和 AQP9。它能够抑制小鼠和人 AQP3,IC50值为 ~0.1-0.4 μM。
T9215 ELOVL6-IN-2

Others Others
ELOVL6-IN-2 是具有口服活性的ELOVL6选择性抑制。它抑制小鼠ELOVL6活性的IC50值为 34 nM。
T9194 UMB298

Epigenetic Reader Domain Chromatin/Epigenetic
UMB298 是一种有效的选择性 CBP/P300 溴结构域抑制剂,抑制 BRD4,IC50 为 5193nM。
T38163 ML-148

Dehydrogenase Metabolism
ML-148 是 15-羟基前列腺素脱氢酶 (15-PGDH, IC50 = 56 nM) 的特异性抑制剂。 ML-148 可用于分析一组相关的脱氢酶或还原酶以及有关前列腺素信号通路的研究。
T9164 BMS-986242

BMS986242

IDO; Indoleamine 2,3-Dioxygenase (IDO) Metabolism
BMS-986242 是具有口服具有活力、强效的、选择性的 indoleamine-2,3-dioxygenase 1 抑制剂,可用于研究癌症。
T9214 ELOVL6-IN-1

Others Others
ELOVL6-IN-1 是一种选择性 ELOVL6抑制剂,口服具有活性。它对丙二酰辅酶 a (Ki:994 nM) 和对棕榈酰辅酶 a 具有非竞争性抑制 ELOVL6 作用。它能够剂量依赖性的一种小鼠 ELOVL6(IC50:0.350 μM)。
T3474 RO 46-8443

Endothelin Receptor GPCR/G Protein
Ro 46-844 是选择性非肽内皮素受体拮抗剂。它对ETB(IC50: 34-69 nM) 的选择性比ETA 受体 (IC50: 6800 nM) 高的100倍以上。
TP1898 HS024

HS 024

Melanocortin Receptor GPCR/G Protein; Neuroscience
HS024 是一种选择性的MC4受体拮抗剂,可增加食物摄入,对 MC4、MC5、MC3 和 MC1 的Ki 分别为 0.29、3.29、5.45 和 18.6 nM。
T8450 TCN 213

TCN213

NMDAR Neuroscience
TCN 213 是一种可克服的(surmountable)、甘氨酸依赖的 GluN1/GluN2A NMDAR 选择性拮抗剂,当甘氨酸的含量为75、 750、7500 nM 时,IC50s 值分别为 0.55、3.5、40 μM。它可用于在药理学上监测 NMDAR 表达在发育中的皮层神经元中的转换。
T22514 4F 4PP oxalate

5-HT Receptor GPCR/G Protein; Neuroscience
4F 4PP oxalate 是一种选择性5-HT2A 拮抗剂。
T4378 MS049

Histone Methyltransferase Chromatin/Epigenetic
MS049 是一种有效的、选择性的和细胞活性的 PRMT4 和 PRMT6 双重抑制剂,IC50 分别为 34 和 43 nM。它可降低 HEK293 细胞的 Med12me2a 和 H3R2me2a 水平。
T4534 BMS-309403

FABP Metabolism
BMS309403 是有效的、选择性脂肪细胞脂肪酸结合蛋白 aFABP 抑制剂。它可改善载脂蛋白 E 缺乏症小鼠和培养的人内皮细胞的内皮功能。它能够与蛋白质内部的脂肪酸结合口袋相互作用,竞争性地抑制内源性脂肪酸的结合。
T11723L JNJ-39758979

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
JNJ-39758979是一种选择性的、高亲和力的、可口服的组胺 H4 受体拮抗剂,具有抗炎和止痒作用,对人、小鼠和猴子的组胺 H4 受体的 Ki 值分别为 12.5、5.3 和 25 nM。它对组胺诱导的 cAMP 抑制作用具有拮抗作用,pA2 为 7.9。
T5436 MZ 1

Epigenetic Reader Domain; PROTACs Chromatin/Epigenetic; PROTAC
MZ 1 是由 von Hippel-Lindau 配体和 BRD4配体相连的 PROTAC,是一种 BRD4 蛋白降解剂。
T23312 SB 204741

5-HT Receptor GPCR/G Protein; Neuroscience
SB 204741 是一种选择性的5-HT2B 拮抗剂,具有高亲和性,pKi 值为7.1。
T15784 LP99

Epigenetic Reader Domain Chromatin/Epigenetic
LP99 是一种表观遗传探针,可破坏 BRD7 和 BRD9 与细胞中染色质的结合。它是一种选择性的 BRD7 和 BRD9 溴结构域抑制剂,对 BRD9 的 Kd 为 99 nM。
T3072 XL019

Apoptosis; FLT; JAK; PDGFR Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
XL019 是一种具有口服活性的选择性JAK2抑制剂。它对JAK2的选择性是 100 多种丝氨酸/苏氨酸和酪氨酸激酶的 50 倍以上。它对 JAK2 V617F 和野生型 JAK2 细胞中 STAT3 和 STAT5 磷酸化有抑制作用。
T3284 Carazolol

Conducton,Suacron,咔唑心安

Adrenergic Receptor GPCR/G Protein; Neuroscience
Carazolol (Suacron) 是高效的 β1/β2 肾上腺素受体拮抗剂,也是高效 β3肾上腺素受体选择性激动剂,可用于高血压的研究。
T36670 JNJ-67856633

MALT Immunology/Inflammation
JNJ-67856633 是口服有效的、选择性的、变构性的 MALT1 protease 抑制剂。在某些情况下,JNJ-67856633可以导致肿瘤停滞。
T16143 MRTX-1257

Ras GPCR/G Protein; MAPK
MRTX-1257 是选择性的、可口服的不可逆共价KRAS G12C 抑制剂,其在 H358 细胞中测得 KRAS 依赖 ERK 磷酸化的IC50值为 900 pM。

化合物

Selective PI3Kδ Inhibitor 1
Cat.No: T5831
Synonym:
Target: PI3K
FKBP51F67V-selective antagonist Ligand2
Cat.No: T79184
Synonym:
Target: FKBP
TRPV2-selective blocker 1
Cat.No: T80930
Synonym:
Target: Others
MPI_5a
Cat.No: T16129
Synonym:
Target: HDAC
ODQ
Cat.No: T19777
Synonym:
Target: Apoptosis, Others, Guanylate cyclase
Metolachlor
Cat.No: T19891
Synonym:
Target: Others
Spastazoline
Cat.No: T8513
Synonym:
Target: Others
THIQ
Cat.No: T8485
Synonym:
Target: Melanocortin Receptor
Bupranolol
Cat.No: T8580
Synonym:
Target: Adrenergic Receptor
Enpatoran
Cat.No: T9570
Synonym:
Target: TLR
HPOB
Cat.No: T2430
Synonym:
Target: Apoptosis, HDAC
5-BDBD
Cat.No: T22518
Synonym:
Target: P2X Receptor
Rhosin hydrochloride
Cat.No: T16745
Synonym:
Target: Apoptosis, Rho, Ras
SGX-523
Cat.No: T2293
Synonym:
Target: Raf, p38 MAPK, c-Met/HGFR, Bcr-Abl
Ofatumumab
Cat.No: T9925
Synonym:
Target: Others
A-366
Cat.No: T3624
Synonym: A 366,A366
Target: Epigenetic Reader Domain, Histone Methyltransferase
LDN-91946
Cat.No: T15729
Synonym:
Target: DUB
GAK inhibitor 49
Cat.No: T8535
Synonym:
Target: Serine/threonin kinase
KEA1-97
Cat.No: T9118
Synonym:
Target: Apoptosis, Others, Caspase
Wiskostatin
Cat.No: T2164
Synonym:
Target: Others
RUVBL1/2 ATPase-IN-1
Cat.No: T9882
Synonym:
Target: Others
PW0787
Cat.No: T9452
Synonym:
Target: GPR
Tetraethylammonium chloride
Cat.No: T7538
Synonym:
Target: Potassium Channel
GSK-114
Cat.No: T22341
Synonym:
Target: Others
Bisindolylmaleimide IV
Cat.No: T7659
Synonym:
Target: Others, PKC
ITI-214
Cat.No: T11689
Synonym: ITI214
Target: PDE
S29434
Cat.No: T7149
Synonym:
Target: NADPH, Autophagy
DQP 1105
Cat.No: T22748
Synonym:
Target: NMDAR
DCLK1-IN-1
Cat.No: T8418
Synonym:
Target: Others
ARS-853
Cat.No: T7414
Synonym:
Target: Apoptosis, Raf, Ras
DFP00173
Cat.No: T11014
Synonym:
Target: Aquaporin
ELOVL6-IN-2
Cat.No: T9215
Synonym:
Target: Others
UMB298
Cat.No: T9194
Synonym:
Target: Epigenetic Reader Domain
ML-148
Cat.No: T38163
Synonym:
Target: Dehydrogenase
BMS-986242
Cat.No: T9164
Synonym: BMS986242
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
ELOVL6-IN-1
Cat.No: T9214
Synonym:
Target: Others
RO 46-8443
Cat.No: T3474
Synonym:
Target: Endothelin Receptor
HS024
Cat.No: TP1898
Synonym: HS 024
Target: Melanocortin Receptor
TCN 213
Cat.No: T8450
Synonym: TCN213
Target: NMDAR
4F 4PP oxalate
Cat.No: T22514
Synonym:
Target: 5-HT Receptor
MS049
Cat.No: T4378
Synonym:
Target: Histone Methyltransferase
BMS-309403
Cat.No: T4534
Synonym:
Target: FABP
JNJ-39758979
Cat.No: T11723L
Synonym:
Target: Histamine Receptor
MZ 1
Cat.No: T5436
Synonym:
Target: Epigenetic Reader Domain, PROTACs
SB 204741
Cat.No: T23312
Synonym:
Target: 5-HT Receptor
LP99
Cat.No: T15784
Synonym:
Target: Epigenetic Reader Domain
XL019
Cat.No: T3072
Synonym:
Target: Apoptosis, FLT, JAK, PDGFR
Carazolol
Cat.No: T3284
Synonym: Conducton,Suacron,咔唑心安
Target: Adrenergic Receptor
JNJ-67856633
Cat.No: T36670
Synonym:
Target: MALT
MRTX-1257
Cat.No: T16143
Synonym:
Target: Ras
Cat. No. Product Name Target Signaling Pathways
TN1120 Osthenol

MAO; Monoamine Oxidase Metabolism; Neuroscience
Osthenol 是一种前酰化香豆素,从独活干根中分离得到。它对重组 hMAO-A 具有潜在的选择性抑制作用,IC50=0.74 µM,对 hMAO-A 和 hMAO-B 表现出较高的选择性指数。它是一种可逆的,选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂 (Ki=0.26 µM)。
T9933 Methyl 2,4-dihydroxyphenylacetate

Others Others
Methyl 2,4-dihydroxyphenylacetate 是从 Nigella damascena 种子中分离得到的天然产物,具有选择性的植物毒性作用。
T5722 Nevadensin

Pedunculin,石吊兰素,5,7-二羟基-6,8,4'-三甲氧基黄酮

Anti-infection; Antibacterial Microbiology/Virology
Nevadensin 是一种重要的草本成分,可抑制雌二醇的生物活化。 它具有抗结核分枝杆菌、镇咳、抗炎、抗高血压等多种药理作用。
T15686 L-741626

3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole

Dopamine Receptor GPCR/G Protein; Neuroscience
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) 是D2多巴胺受体选择性拮抗剂,对人 D2、D3 和 D4 受体的Ki 分别为 2.4、100 和 220 nM。
T23119 Palmitoylisopropylamide

FAAH Metabolism; Neuroscience
Palmitoylisopropylamide 是一种选择性 FAAH 抑制剂,抑制[H]-AEA摄取,在低浓度下抑制细胞增殖。
Fr12415 Ethyl 4-hydroxyphenylacetate

Others Others
Ethyl 4-hydroxyphenylacetate 是单胺氧化酶 A 的选择性抑制剂。
TN1731 Hernandezine

TNF; ROS; P-gp; AMPK Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; PI3K/Akt/mTOR signaling
Hernandezine 是 AMPK 激动剂的激动剂,也是癌细胞中 ABCB1 介导的 MDR 的特异性逆转剂。
T5838 L-Canavanine sulfate

NO Synthase; NOD Immunology/Inflammation; NF-κB
L-Canavanine sulfate 是一种诱导型 NO 合酶的选择性抑制剂。
T13475 β-Aminopropionitrile

3-氨基丙腈,3-Aminopropionitrile,BAPN

Others; Endogenous Metabolite Metabolism; Others
β-Aminopropionitrile (3-Aminopropionitrile) 是赖氨酰氧化酶的特异性抑制剂。
TN4171 Grossamide

NO Synthase Immunology/Inflammation
Grossamide (GSE) 是一种来自虎杖的木脂酰胺。Grossamide 具有抗炎症活性,可通过上调精氨酸酶和下调诱导型一氧化氮合酶来抑制精氨酸产生一氧化氮(NO),抑制NO对OXPHOS的抑制作用。
T2266 SantacruzaMate A

CAY-10683

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
SantacruzaMate A (CAY-10683) 是一种高效选择性的HDAC2抑制剂,IC50为 119 pM。
TQ0203 Tafluprost

MK2452,AFP-168,他氟前列素

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Tafluprost 是一种抗青光眼前列腺素(PG)类似物。
T8035 3'-Methoxyflavonol

NMU2R Neuroscience
3'-Methoxyflavonol 是一种神经介肽 U 2 受体的选择性激动剂。
T3432 Cinobufagin

华蟾蜍精,华蟾酥毒基,Cinobufagine

Apoptosis; ATPase; Autophagy Apoptosis; Autophagy; Membrane transporter/Ion channel
Cinobufagin (Cinobufagine) 是一种具有抗肿瘤功效的天然产物。
T8299 Dimethyl lithospermate B

丹酚酸B二甲酯,dmLSB

Sodium Channel Membrane transporter/Ion channel
Dimethyl lithospermate B (dmLSB) 是 Na+通道的选择性激动剂,减缓钠电流 (INa) 失活,导致动作电位 (AP) 早期内向电流增加。
TN2202 Sempervirine

常绿钩吻碱

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Sempervirine 可以解开环状 DNA,它显示出选择性抑制癌症 DNA 的体外合成。
T6995 Ochromycinone

STA 21,STA21,STA-21

Antibacterial; STAT JAK/STAT signaling; Microbiology/Virology; Stem Cells
Ochromycinone (STA 21) 是一种天然抗生素,也是一种 STAT3抑制剂。它可抑制 STAT3DNA 结合活性,STAT3二聚化。它具有抗癌和抗菌活性。
T4643 TFAP

N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide

COX; Endogenous Metabolite Immunology/Inflammation; Metabolism; Neuroscience
TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) 是环氧酶 1 的一种选择性抑制剂,IC50值为 0.8 μM。
T1680 Tolazoline hydrochloride

Imidaline hydrochloride,苯甲唑啉盐酸盐,Imidaline (hydrochloride),Benzidazol hydrochloride,Tolazoline HCl,NSC35110 (hydrochloride)

Adrenergic Receptor GPCR/G Protein; Neuroscience
Tolazoline hydrochloride (NSC35110(hydrochloride)) 是一种 α 肾上腺素受体抑制剂。
TN1817 Kaempferol 3,7,4'-trimethyl ether

莰非醇-3,7,4'-三甲醚,莰非醇三甲醚,Kaempferol 3,7,4'-trimethylether

NO Synthase Immunology/Inflammation
Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) 是一种黄酮醇苷元,从 Siparuna gigantotepala 中分离得到,具有抗氧化作用。
T4S1521 1,4-Dicaffeoylquinic acid

1,4-二咖啡酰奎宁酸,洋蓟素

HIV Protease Microbiology/Virology; Proteases/Proteasome
1,4-Dicaffeoylquinic acid 是一种苯丙素类物质,从苍耳子中获得,可以减少 LPS 诱导的 TNF-α 的生成,具有抗炎活性。
T17310 Phenylephrine

去氧肾上腺素,L-Phenylephrine,去氧肾上腺素碱,(R)-(-)-Phenylephrine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Phenylephrine ((R)-(-)-Phenylephrine) 是一种选择性的α1-肾上腺素受体激动剂,常用作减充血剂。
T8125 Quinidine sulfate dihydrate

硫酸奎尼宁,硫酸奎尼丁二水合物,Chinidin Sodium,β-quinine Sodium,Pitayine Sodium,Quinidine sulfate

P450 Metabolism
Quinidine sulfate dihydrate (Pitayine Sodium) 是抗心律失常剂,能够阻断 K+通道(IC50:19.9 μM)。它是细胞色素 P450db 的选择性抑制剂,可用于研究疟疾。
TQ0196 Cucurbitacin I

NSC-521777,JSI-124,Elatericin B,葫芦素 I

JAK; STAT Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
Cucurbitacin I (JSI-124) 是从曲莲中提取的一种天然产物,是 JAK2/STAT3选择性抑制剂,有抗肿瘤活性。
T8187 Tetrahydroepiberberine

Others; Influenza Virus; Antifungal Microbiology/Virology; Others
Tetrahydroepiberberine 是从Corydalis impatiens(Pall) 中分离得到的一种异喹啉生物碱,具有抗真菌和选择性抑制 PI-3 病毒活性的作用。
T5743 Gymnemagenin

Liver X Receptor Metabolism
Gymnemagenin 是一种分离自G. sylvestre 的三萜。 它具有抗病毒作用,对糖尿病和肥胖症具有潜在的研究价值。
TN2107 Protoescigenin

Others Others
Protoescigenin 来自七叶树皂甙混合物,可用作用于选择性保护的探索性化学的底物。
TN4618 N-trans-Sinapoyltyramine

Others Others
N-trans-Sinapoyltyramine 对 HeLa 人癌细胞系表现出强烈的选择性细胞毒性,IC50 值为 9.77 ± 1.25 μm。
T2922 Phlorizin

Floridzin,根皮甙,根皮苷,NSC 2833,Phloridzin

ATPase; SGLT GPCR/G Protein; Membrane transporter/Ion channel
Phlorizin (Phloridzin) 是非选择性的SGLT 抑制剂,也是Na+/K+-ATPase 抑制剂,对于hSGLT1和hSGLT2的Ki 值分别为 300 和 39 nM。
TN1490 Chrysoeriol

ERK; p38 MAPK; Akt Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Chrysoeriol 是一种天然黄酮,可从热带植物Coronopus didymus 中提取获得,具有强大的抗氧化功能,能够抑制脂质的过氧化。
T21581L AC 187 Acetate

AC 187 Acetate (151804-77-2 Free base)

Amylin Receptor GPCR/G Protein
AC 187 Acetate 是胰淀素受体的强效拮抗剂。AC 187 对胰淀素受体的选择性高于降钙素和 CGRP 受体。
TQ0274 27-Hydroxycholesterol

27-羟基胆固醇,5,25R-胆甾烯-3BETA,26-二醇,25(R)-27-hydroxy Cholesterol

Estrogen/progestogen Receptor; Liver X Receptor Endocrinology/Hormones; Metabolism
27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) 是一种有效的、选择性的雌激素受体调节剂和肝X 受体激动剂。
T3325 Liquiritigenin

4',7-Dihydroxyflavanone,甘草素

Estrogen Receptor/ERR; Estrogen/progestogen Receptor Endocrinology/Hormones
Liquiritigenin (4',7-Dihydroxyflavanone) 是一种黄烷酮,从甘草中分离得到,是高度选择性的雌激素受体β 激动剂,用于活化 ERE tk-Luc 的 EC50值为36.5 nM。
T1186 Ifenprodil Tartrate

Potassium Channel; NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
Ifenprodil tartrate 是典型的非竞争性 NMDA 受体拮抗剂,抑制 GIRK (Kir3),通过基底 GIRK 活性减少内向电流,有用做脑血管舒张试剂的潜力。它对 NR1A/NR2B 受体亲和力是 NR1A/NR2A 受体的 400 倍。
TQ0288 Hexahydrocurcumin

Reactive Oxygen Species; ROS; COX Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Hexahydrocurcumin 是一种选择性口服活性COX-2抑制剂,对 COX-1 无活性,是姜黄素的主要代谢产物之一,。它具有抗氧化,抗癌和抗炎作用。
T7607 PSI-6130

R 1656,2'-去氧-2'-氟-2'-C-甲基胞苷

HCV Protease Microbiology/Virology; Proteases/Proteasome
PSI-6130 (R 1656) 是高效选择性 HCV NS5B 聚合酶抑制剂,抑制 HCV 复制,IC50值为 0.6 μM。
TMA1122 N-Feruloylserotonin

(E/Z)-Moschamine,Moschamine

Antioxidant oxidation-reduction
N-Feruloylserotonin ((E/Z)-Moschamine) 是可从 Carthamus tinctorius L. 中分离得到的一种血清素衍生物,具有抗氧化活性,有用于动脉粥样硬化和主动脉壁膨胀研究的潜能。
T17048 Tetradecanoylcarnitine

L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine

Endogenous Metabolite Metabolism
Tetradecanoylcarnitine (L-Myristoylcarnitine) 是一种酰基肉碱,参与长链脂肪酸的β-氧化,是极长链酰辅酶A脱氢酶缺乏症的一种潜在标记物。
T6841 Fumagillin

NSC9168,烟曲霉素,Amebacilin

Others; HIV Protease; Antibiotic; Parasite Microbiology/Virology; Others; Proteases/Proteasome
Fumagillin (Amebacilin) 由烟曲霉菌中提取的一种抗菌药,有抗阿米巴活性。它通过抑制 HIV-1 viral protein R 活性来抑制 HIV‐1感染。
T0505 Methyldopa

L-(-)-α-Methyldopa,MK-351,甲基多巴

Dopamine Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
L-(-)-α-Methyldopa (MK-351) 是一种前药,在中枢神经系统中被代谢成 α-Methylepinephrine。它是 α-肾上腺素能激动剂,对 α2- adrenergic receptors 有选择性。
T8895 Altenusin

FXR Metabolism
Altenusin 是天然的非甾体真菌代谢物,是新型 FXR 选择性激动剂,EC50 值为 3.2 ± 0.2 μM。它具有明显的 DPPH 自由基清除活性。
T0453 Phenylephrine hydrochloride

NCI-c55641,Phenylephrine HCl,盐酸去氧肾上腺素,(R)-(-)-Phenylephrine hydrochloride

Endogenous Metabolite; Adrenergic Receptor GPCR/G Protein; Metabolism; Neuroscience
Phenylephrine hydrochloride (NCI-c55641) 是选择性的α1-肾上腺素能受体激动剂,对α1A,α1B 和α1D 受体的pKis 分为4.70,4.87和5.86。
T0167 Vinpocetine

长春西丁,RGH-4405,长春西汀,Ethyl apovincaminate

IκB/IKK; NF-κB; Sodium Channel; PDE Membrane transporter/Ion channel; Metabolism; NF-κB
Vinpocetine (RGH-4405) 是一种长春花生物碱衍生物,是阻断 Na+通道的阻断剂。Vinpocetine 抑制IKK 的IC50为 17.17 μM。Vinpocetine 也是PDE 抑制剂,并通过直接靶向IKK 抑制NF-κB 依赖性炎症反应,已被广泛用于研究脑血管疾病。
T1125 Shikonin

NSC 252844,Isoarnebin 4,(+)-Shikonin,紫草素,Alkanna Red,C.I. 75535,Anchusa acid

TNF; NF-κB; Chloride channel; HIV Protease; PKM Apoptosis; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Shikonin (Anchusa acid) 属于天然产物,是一种 TMEM16A 氯离子通道抑制剂 (IC50=6.5 μM) 和选择性 PKM2 抑制剂。Shikonin 具有抗肿瘤、抗炎和伤口愈合活性。
TN2252 Syrosingopine

Dopamine Receptor GPCR/G Protein; Neuroscience
Syrosingopine 是 MCT1和 MCT4双重抑制剂,对 MCT4 的效力高 60 倍,可防止乳酸和 H+ 流出。它是可口服抗高血压药物,联合二甲双胍具有研究癌症疾病的潜力。
TN7121 d-Epigalbacin

(-)-Zuonin A,表加巴辛

JNK MAPK
d-Epigalbacin ((-)-Zuonin A) 是一种天然木质素。d-Epigalbacin 是一种强效、选择性的JNKs 抑制剂,JNK1、JNK2和JNK3的IC50s 分别为1.7μM、2.9μM 和1.74μM。
T21344 1-Deoxynojirimycin hydrochloride

Moranoline,去氧野艽霉素盐酸盐,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin

PI3K; Antibacterial; Antibiotic; Glucosidase Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling
1-Deoxynojirimycin hydrochloride (Moranoline) 是一种口服有效的 α-葡萄糖苷酶抑制剂,具有降血糖、减肥和抗病毒的作用,可抑制餐后血糖,预防糖尿病。
TN6739 Angoline

6-Methoxyldihydrochelerythrine

IL Receptor; STAT Immunology/Inflammation; JAK/STAT signaling; Stem Cells
Angoline (6-Methoxyldihydrochelerythrine) 是选择性 IL6/STAT3信号通路的抑制剂,IC50为 11.56 μM。它抑制 STAT3 磷酸化及其靶基因表达,并抑制癌细胞增殖。
T6648 Rotundine

Gindarine,L-Tetrahydropalmatine,Caseanine,罗通定,(-)-Tetrahydropalmatine

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
Rotundine (Gindarine) 是多巴胺D1、D2和D3受体的拮抗剂,IC50值分别为 166、1.4 和 3.3 μM。 它也是5-HT1A 的拮抗剂,IC50值为 370 nM。
T0906 Salinomycin

盐霉素,Procoxacin

Wnt/beta-catenin; Antibacterial Cytoskeletal Signaling; Microbiology/Virology; Stem Cells
Salinomycin (Procoxacin)是一种多醚类钾离子载体抗生素,特异性抑制革兰氏阳性细菌生长。Salinomycin 作为Wnt/β-连环蛋白信号通路的有效抑制剂,阻断Wnt诱导的LRP6磷酸化。此外,Salinomycin (Procoxacin)对人类癌症干细胞显示出选择性活性。
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天然产物

Osthenol
Cat.No: TN1120
Synonym:
Target: MAO, Monoamine Oxidase
Methyl 2,4-dihydroxyphenylacetate
Cat.No: T9933
Synonym:
Target: Others
Nevadensin
Cat.No: T5722
Synonym: Pedunculin,石吊兰素,5,7-二羟基-6,8,4'-三甲氧基黄酮
Target: Anti-infection, Antibacterial
L-741626
Cat.No: T15686
Synonym: 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
Target: Dopamine Receptor
Palmitoylisopropylamide
Cat.No: T23119
Synonym:
Target: FAAH
Ethyl 4-hydroxyphenylacetate
Cat.No: Fr12415
Synonym:
Target: Others
Hernandezine
Cat.No: TN1731
Synonym:
Target: TNF, ROS, P-gp, AMPK
L-Canavanine sulfate
Cat.No: T5838
Synonym:
Target: NO Synthase, NOD
β-Aminopropionitrile
Cat.No: T13475
Synonym: 3-氨基丙腈,3-Aminopropionitrile,BAPN
Target: Others, Endogenous Metabolite
Grossamide
Cat.No: TN4171
Synonym:
Target: NO Synthase
SantacruzaMate A
Cat.No: T2266
Synonym: CAY-10683
Target: HDAC
Tafluprost
Cat.No: TQ0203
Synonym: MK2452,AFP-168,他氟前列素
Target: Prostaglandin Receptor
3'-Methoxyflavonol
Cat.No: T8035
Synonym:
Target: NMU2R
Cinobufagin
Cat.No: T3432
Synonym: 华蟾蜍精,华蟾酥毒基,Cinobufagine
Target: Apoptosis, ATPase, Autophagy
Dimethyl lithospermate B
Cat.No: T8299
Synonym: 丹酚酸B二甲酯,dmLSB
Target: Sodium Channel
Sempervirine
Cat.No: TN2202
Synonym: 常绿钩吻碱
Target: DNA/RNA Synthesis
Ochromycinone
Cat.No: T6995
Synonym: STA 21,STA21,STA-21
Target: Antibacterial, STAT
TFAP
Cat.No: T4643
Synonym: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
Target: COX, Endogenous Metabolite
Tolazoline hydrochloride
Cat.No: T1680
Synonym: Imidaline hydrochloride,苯甲唑啉盐酸盐,Imidaline (hydrochloride),Benzidazol hydrochloride,Tolazoline HCl,NSC35110 (hydrochloride)
Target: Adrenergic Receptor
Kaempferol 3,7,4'-trimethyl ether
Cat.No: TN1817
Synonym: 莰非醇-3,7,4'-三甲醚,莰非醇三甲醚,Kaempferol 3,7,4'-trimethylether
Target: NO Synthase
1,4-Dicaffeoylquinic acid
Cat.No: T4S1521
Synonym: 1,4-二咖啡酰奎宁酸,洋蓟素
Target: HIV Protease
Phenylephrine
Cat.No: T17310
Synonym: 去氧肾上腺素,L-Phenylephrine,去氧肾上腺素碱,(R)-(-)-Phenylephrine
Target: Adrenergic Receptor
Quinidine sulfate dihydrate
Cat.No: T8125
Synonym: 硫酸奎尼宁,硫酸奎尼丁二水合物,Chinidin Sodium,β-quinine Sodium,Pitayine Sodium,Quinidine sulfate
Target: P450
Cucurbitacin I
Cat.No: TQ0196
Synonym: NSC-521777,JSI-124,Elatericin B,葫芦素 I
Target: JAK, STAT
Tetrahydroepiberberine
Cat.No: T8187
Synonym:
Target: Others, Influenza Virus, Antifungal
Gymnemagenin
Cat.No: T5743
Synonym:
Target: Liver X Receptor
Protoescigenin
Cat.No: TN2107
Synonym:
Target: Others
N-trans-Sinapoyltyramine
Cat.No: TN4618
Synonym:
Target: Others
Phlorizin
Cat.No: T2922
Synonym: Floridzin,根皮甙,根皮苷,NSC 2833,Phloridzin
Target: ATPase, SGLT
Chrysoeriol
Cat.No: TN1490
Synonym:
Target: ERK, p38 MAPK, Akt
AC 187 Acetate
Cat.No: T21581L
Synonym: AC 187 Acetate (151804-77-2 Free base)
Target: Amylin Receptor
27-Hydroxycholesterol
Cat.No: TQ0274
Synonym: 27-羟基胆固醇,5,25R-胆甾烯-3BETA,26-二醇,25(R)-27-hydroxy Cholesterol
Target: Estrogen/progestogen Receptor, Liver X Receptor
Liquiritigenin
Cat.No: T3325
Synonym: 4',7-Dihydroxyflavanone,甘草素
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
Ifenprodil Tartrate
Cat.No: T1186
Synonym:
Target: Potassium Channel, NMDAR, iGluR
Hexahydrocurcumin
Cat.No: TQ0288
Synonym:
Target: Reactive Oxygen Species, ROS, COX
PSI-6130
Cat.No: T7607
Synonym: R 1656,2'-去氧-2'-氟-2'-C-甲基胞苷
Target: HCV Protease
N-Feruloylserotonin
Cat.No: TMA1122
Synonym: (E/Z)-Moschamine,Moschamine
Target: Antioxidant
Tetradecanoylcarnitine
Cat.No: T17048
Synonym: L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine
Target: Endogenous Metabolite
Fumagillin
Cat.No: T6841
Synonym: NSC9168,烟曲霉素,Amebacilin
Target: Others, HIV Protease, Antibiotic, Parasite
Methyldopa
Cat.No: T0505
Synonym: L-(-)-α-Methyldopa,MK-351,甲基多巴
Target: Dopamine Receptor, Adrenergic Receptor
Altenusin
Cat.No: T8895
Synonym:
Target: FXR
Phenylephrine hydrochloride
Cat.No: T0453
Synonym: NCI-c55641,Phenylephrine HCl,盐酸去氧肾上腺素,(R)-(-)-Phenylephrine hydrochloride
Target: Endogenous Metabolite, Adrenergic Receptor
Vinpocetine
Cat.No: T0167
Synonym: 长春西丁,RGH-4405,长春西汀,Ethyl apovincaminate
Target: IκB/IKK, NF-κB, Sodium Channel, PDE
Shikonin
Cat.No: T1125
Synonym: NSC 252844,Isoarnebin 4,(+)-Shikonin,紫草素,Alkanna Red,C.I. 75535,Anchusa acid
Target: TNF, NF-κB, Chloride channel, HIV Protease, PKM
Syrosingopine
Cat.No: TN2252
Synonym:
Target: Dopamine Receptor
d-Epigalbacin
Cat.No: TN7121
Synonym: (-)-Zuonin A,表加巴辛
Target: JNK
1-Deoxynojirimycin hydrochloride
Cat.No: T21344
Synonym: Moranoline,去氧野艽霉素盐酸盐,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin
Target: PI3K, Antibacterial, Antibiotic, Glucosidase
Angoline
Cat.No: TN6739
Synonym: 6-Methoxyldihydrochelerythrine
Target: IL Receptor, STAT
Rotundine
Cat.No: T6648
Synonym: Gindarine,L-Tetrahydropalmatine,Caseanine,罗通定,(-)-Tetrahydropalmatine
Target: Dopamine Receptor, 5-HT Receptor
Salinomycin
Cat.No: T0906
Synonym: 盐霉素,Procoxacin
Target: Wnt/beta-catenin, Antibacterial
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Cat. No. Product Name Species Expression System
TMPH-02112 SMUG1 Protein, Human, Recombinant (His & SUMO)

Single-strand selective monofunctional uracil DNA g...

Human E. coli
SMUG1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.6 kDa and the accession number is Q53HV7.
TMPH-01392 GRIA2 Protein, Human, Recombinant (His & Myc)

GRIA2,Glutamate receptor ionotropic, AMPA 2,Glutamate recept...

Human E. coli
GRIA2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 63.3 kDa and the accession number is P42262.
TMPH-01393 GRIA3 Protein, Human, Recombinant (His & SUMO)

AMPA-selective glutamate receptor 3,GRIA3,Glutamate...

Human E. coli
GRIA3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 28.0 kDa and the accession number is P42263.
TMPJ-01068 FKBP25/FKBP3 Protein, Human, Recombinant (His)

25 kDa FKBP,FKBP-3,Peptidyl-prolyl cis-trans isomerase FKBP3...

Human E. coli
FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a...
TMPY-02292 IGSF11 Protein, Human, Recombinant (His)

CT119,immunoglobulin superfamily, member 11,BT-IgSF,Igsf13,C...

Human HEK293 Cells
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to overexpressed in colorectal cancers and hep...
TMPY-01460 ABHD4 Protein, Human, Recombinant (His)

abhydrolase domain containing 4,ABH4

Human Baculovirus Insect Cells
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipa...
TMPH-03043 PIA Protein, MenB, Recombinant (His)

Major outer membrane protein P.IA,Class 1 protein,porA

MenB E. coli
Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity.
TMPH-00108 UBC11 Protein, Arabidopsis thaliana, Recombinant (His)

Ubiquitin-conjugating enzyme E2-17 kDa 11,Ubiquitin-conjugat...

Arabidopsis thaliana E. coli
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC11 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.6 kDa and the accession number is P35134.
TMPH-00107 UBC10 Protein, Arabidopsis thaliana, Recombinant (His)

Ubiquitin carrier protein 10/12,Ubiquitin-conjugating enzyme...

Arabidopsis thaliana E. coli
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC10 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.6 kDa and the accession number is P35133.
TMPY-04904 Zika virus (ZIKV) (strain Zika SPH2015) M/Membrane protein (Fc)

ZIKV HEK293 Cells
Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibitors can block the apoptosis induced by ZIKV-M in hNPCs.
TMPH-01693 MAP3K14 Protein, Human, Recombinant (His & Myc)

MAP3K14,Serine/threonine-protein kinase NIK,NF-kappa-beta-in...

Human E. coli
Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
TMPH-01816 OX1R Protein, Human, Recombinant (His & SUMOstar)

Hypocretin receptor type 1,Orexin receptor type 1,Orexin/Hyp...

Human P. pastoris (Yeast)
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. OX1R Protein, Human, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 21.4 kDa and the accession number is O43613.
TMPH-00109 UBC8 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

E2 ubiquitin-conjugating enzyme 8,Ubiquitin carrier protein ...

Arabidopsis thaliana E. coli
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC8 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.0 kDa and the accession number is P35131.
TMPH-03174 LecA Protein, Pseudomonas aeruginosa, Recombinant (His)

lecA,PA-I galactophilic lectin,Galactose-binding lectin

Pseudomonas aeruginosa E. coli
D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. LecA Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.8 kDa and the accession number is Q05097.
TMPH-00379 MLCK Protein, Chicken, Recombinant (His & Myc & SUMO)

Mylk,Telokin,Myosin light chain kinase, smooth muscle

Chicken E. coli
Phosphorylates a specific serine in the N-terminus of a myosin light chain, which leads to the formation of calmodulin/MLCK signal transduction complexes which allow selective transduction of calcium signals. MLCK Protein, Chicken, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 52.9 kDa and the accession number is P11799.
TMPJ-00273 IGSF11 Protein, Human, Recombinant (hFc)

CXADRL1,BT-IgSF,CT119,Igsf13,VSIG3

Human HEK293 Cells
Immunoglobulin superfamily member 11(IGSF11) is abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.IGSF11 functions as a cell adhesion molecule through homophilic interaction and can also stimulates cell growth.IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions.
TMPH-01684 MAP1LC3C Protein, Human, Recombinant (His)

MAP1A/MAP1B light chain 3 C,Microtubule-associated protein 1...

Human E. coli
Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins. MAP1LC3C Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 20.7 kDa and the accession number is Q9BXW...
TMPH-02905 TRPC1 Protein, Mouse, Recombinant (His)

Transient receptor protein 1,Short transient receptor potent...

Mouse E. coli
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. TRPC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 94.0 kDa and the accession number is Q61056.
TMPK-00564 TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)

TBP1,TNF-RI,TNFAR,p55,p60,p55-R,TNF-R55,FPF,TNF-R1,TNFR1-d2,...

Cynomolgus HEK293 Cells
Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling.
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-1,CD331,FGFR-1

Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ...
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)

CD331,FGFR-1,FLT-2,BFGFR,N-sam,FGFR1 β (IIIc),bFGF-R-1

Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb...
TMPJ-01221 UBE2J2 Protein, Human, Recombinant (GST)

NCUBE-2,UBE2J2,Ubiquitin-Conjugating Enzyme E2 J2,NCUBE2,Non...

Human E. coli
Ubiquitin-Conjugating Enzyme E2 J2 (UBE2J2) belongs to the ubiquitin-conjugating enzyme family. UBE2J2 is involved in the ubiquitiantion. UBE2J2 located in the membrane of the endoplasmic reticulum, catalyzes the covalent attachment of ubiquitin to other proteins. UBE2J2 may play a important role in the selective degradation of misfolded membrane protein from the endoplasmic reticulum.
TMPH-03606 P3H 1 Protein, Streptomyces sp., Recombinant (His & Myc)

Proline 3-hydroxylase type I,L-proline cis-3-hydroxylase 1,P...

Streptomyces E. coli
Dioxygenase that catalyzes the 2-oxoglutarate-dependent selective hydroxylation of free L-proline to cis-3-hydroxy-L-proline (cis-3-Hyp). D-proline, trans-4-hydroxy-L-proline, cis-4-hydroxy-L-proline, cis-4-hydroxy-D-proline, and 3,4-dehydro-DL-proline are not substrates. P3H 1 Protein, Streptomyces sp., Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.0 kDa and the accession number is P96010.
TMPH-03390 TRPV2 Protein, Rat, Recombinant (His)

Transient receptor potential cation channel subfamily V memb...

Rat E. coli
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. TRPV2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 88.2 kDa and th...
TMPK-00171 TRAIL Trimer Protein, Human, Recombinant (His & Flag)

TRAIL,Apo-2L,APO2L,TL2,Apo-2 ligand,CD253,TNFSF10

Human HEK293 Cells
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the TRAIL pathway in inducing tumor-selective apoptosis leads to the development of TRAIL-based cancer therapies, which include recombinant forms of TRAIL, TRAIL receptor agonists, and other therapeutic agents.
TMPH-02118 SCN1A Protein, Human, Recombinant (His)

Sodium channel protein brain I subunit alpha,Sodium channel ...

Human E. coli
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Plays a key role in brain, probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neur...
TMPY-05003 GLTP Protein, Human, Recombinant (His)

glycolipid transfer protein

Human HEK293 Cells
Glycolipid transfer proteins (GLTPs) originally were identified as small (~24 kDa), soluble, amphitropic proteins that specifically accelerate the intermembrane transfer of glycolipids. Human GLTP-motifs have evolved to function not only as glucosylceramide binding/transferring domains for phosphoinositol 4-phosphate adaptor protein-2 during glycosphingolipid biosynthesis but also as selective binding/transfer proteins for ceramide-1-phosphate. Glycolipid transfer protein (GLTP) accelerates glyc...
TMPJ-00891 Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

hGK-1,Kallikrein-2,Tissue Kallikrein-2,KLK2,Glandular Kallik...

Human HEK293 Cells
Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 ...
TMPJ-01363 CLIC5 Protein, Human, Recombinant (His)

Chloride Intracellular Channel Protein 5,CLIC5

Human E. coli
Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 can insert into membranes and form selective ion channels regulated by actin that may transport chloride ions. It may play a role in the regulation of transepithelial ion absorption and secretion. CLIC5 specif...
TMPH-02365 JC polyomavirus (JCV) Minor capsid protein VP2 (His)

Minor capsid protein VP2,Minor structural protein VP2

JCPyV E. coli
Isoform VP2 is a structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers. Participates in host cell receptor binding together with VP1. Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane. Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm. Nuclear entry of the viral DNA ...
TMPH-02347 Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His)

Matrix protein 2,Proton channel protein M2,M

H1N1 E. coli
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins ...
TMPH-02348 Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc)

Matrix protein 2,M,Proton channel protein M2

H1N1 E. coli
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins ...
TMPH-02301 VPS35 Protein, Human, Recombinant (His & Myc)

VPS35,Vacuolar protein sorting-associated protein 35,Vesicle...

Human E. coli
Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of...
TMPH-00789 Hamster polyomavirus (HaPyV) VP1 Protein (His & Myc)

Major structural protein VP1,Major capsid protein VP1

HaPyV E. coli
Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with sialic acids on the cell surface to provide virion attachment to target cell. Once attached, the virion is internalized by endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby...
TMPH-00201 BK polyomavirus (BKPyV) VP2 Protein (His)

Minor capsid protein VP2,Minor structural protein VP2

BKPyV E. coli
Isoform VP2 is a structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers. Participates in host cell receptor binding together with VP1. Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane. Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm. Nuclear entry of the viral DNA ...
TMPY-01812 Enoyl-ACP Reductase Protein, E. coli, Recombinant (His)

b1288,JW1281,gts,ECK1283,qmeA,envM

E. coli E. coli
Enoyl-ACP reductase, also known as NADH-dependent enoyl-ACP reductase and FABI, is a cell inner membrane and peripheral membrane protein which belongs to theshort-chain dehydrogenases/reductases (SDR) family and FabI subfamily. Microorganisms produce many kinds of antibiotics which function in an antagonistic capacity in nature where they have much competition. Bacterial FAS provides essential fatty acids for use in the assembly of key cellular components. Among them, FABI is an enoyl-ACP...
TMPH-02803 NRROS Protein, Mouse, Recombinant (His)

Negative regulator of reactive oxygen species,Transforming g...

Mouse E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1. TGF-beta-1 activation mediated by LRRC33/NRROS is highly localized: there is little spreading of TGF-beta-1 acti...
TMPH-01516 FCGRT Protein, Human, Recombinant (His)

Neonatal Fc receptor,IgG receptor FcRn large subunit p51,FCG...

Human HEK293 Cells
Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and exten...
TMPH-01517 FCGRT Protein, Human, Recombinant (GST)

IgG Fc fragment receptor transporter alpha chain,Neonatal Fc...

Human E. coli
Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and exten...
TMPY-02842 UBE2L6 Protein, Human, Recombinant (His)

UBCH8,ubiquitin-conjugating enzyme E2L 6,RIG-B

Human E. coli
UBCH8, also known as UBE2L6, belongs to the ubiquitin-conjugating enzyme family. The family of ubiquitin-conjugating (E2) enzymes is characterized by the presence of a highly conserved ubiquitin-conjugating (UBC) domain. These domains accommodate the ATP-activated ubiquitin (Ub) or ubiquitin-like (UBL) protein via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the E1 and E3 enzymes and connect activation to covalent modi...
TMPJ-00782 Amyloid Precursor Protein, Human, Recombinant (hFc)

Amyloid Precursor,Amyloid Precursor Protein 695,APP695

Human HEK293 Cells
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Of the three major splice isoforms of APP (APP695, APP751, and APP770) APP695 is the predominant neuronal form from which Amyloid beta peptide and transcriptionally-active cleaved intracellular domain of APP (AICD) are preferentially generated by selective process...
TMPY-04402 CSNK1G1 Protein, Human, Recombinant (His & GST)

CK1γ1,casein kinase 1, gamma 1,casein kinase 1, γ1,CK1gamma1

Human Baculovirus Insect Cells
Casein kinase I isoform gamma-1, also known as CSNK1G1, is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Thecasein kinase I family of protein kinases are serine / threonine-selective enzymes that function as regulators ofsignal transductionpathways in most eukaryotic cell types. Casein has been used as a substrate since the earliest days of research on protein phosphorylation. Casein kinase activity associated with the endopla...
TMPY-04554 JNK1 Protein, Human, Recombinant (GST)

PRKM8,JNK,JNK-46,JNK21B1/2,JNK1A2,mitogen-activated protein ...

Human Baculovirus Insect Cells
Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. The protein kinases JNK1 has been found to serve as critical molecular links between obesity, metabolic inflammation, and disorders of glucose homeostasis. It is critically involved in ...
TMPY-00564 MCP-4 Protein, Human, Recombinant (His)

MCP-4,CCL13,SCYL1,NCC-1,MCP4,NCC1,CKb10,SCYA13,chemokine (C-...

Human P. pastoris (Yeast)
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chem...
TMPY-01187 Rac1 Protein, Human, Recombinant (GST)

Rac-1,p21-Rac1,MIG5,ras-related C3 botulinum toxin substrate...

Human Baculovirus Insect Cells
RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for RAC1 gene. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, bind...
TMPH-00616 DNA-binding protein H-NS Protein, E. coli, Recombinant (His)

hns,DNA-binding protein H-NS,Protein B1,Protein H1,Heat-stab...

E. coli E. coli
A DNA-binding protein implicated in transcriptional repression (silencing). Also involved in bacterial chromosome organization and compaction. H-NS binds tightly to AT-rich dsDNA and inhibits transcription. Binds upstream and downstream of initiating RNA polymerase, trapping it in a loop and preventing transcription. Binds to hundreds of sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Many of these loci were horizontally transfe...

重组蛋白

SMUG1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02112
Species: Human
Expression System: E. coli
GRIA2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01392
Species: Human
Expression System: E. coli
GRIA3 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01393
Species: Human
Expression System: E. coli
FKBP25/FKBP3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01068
Species: Human
Expression System: E. coli
IGSF11 Protein, Human, Recombinant (His)
Cat.No: TMPY-02292
Species: Human
Expression System: HEK293 Cells
ABHD4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01460
Species: Human
Expression System: Baculovirus Insect Cells
PIA Protein, MenB, Recombinant (His)
Cat.No: TMPH-03043
Species: MenB
Expression System: E. coli
UBC11 Protein, Arabidopsis thaliana, Recombinant (His)
Cat.No: TMPH-00108
Species: Arabidopsis thaliana
Expression System: E. coli
UBC10 Protein, Arabidopsis thaliana, Recombinant (His)
Cat.No: TMPH-00107
Species: Arabidopsis thaliana
Expression System: E. coli
Zika virus (ZIKV) (strain Zika SPH2015) M/Membrane protein (Fc)
Cat.No: TMPY-04904
Species: ZIKV
Expression System: HEK293 Cells
MAP3K14 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01693
Species: Human
Expression System: E. coli
OX1R Protein, Human, Recombinant (His & SUMOstar)
Cat.No: TMPH-01816
Species: Human
Expression System: P. pastoris (Yeast)
UBC8 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Cat.No: TMPH-00109
Species: Arabidopsis thaliana
Expression System: E. coli
LecA Protein, Pseudomonas aeruginosa, Recombinant (His)
Cat.No: TMPH-03174
Species: Pseudomonas aeruginosa
Expression System: E. coli
MLCK Protein, Chicken, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-00379
Species: Chicken
Expression System: E. coli
IGSF11 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00273
Species: Human
Expression System: HEK293 Cells
MAP1LC3C Protein, Human, Recombinant (His)
Cat.No: TMPH-01684
Species: Human
Expression System: E. coli
TRPC1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02905
Species: Mouse
Expression System: E. coli
TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00564
Species: Cynomolgus
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00394
Species: Human
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00392
Species: Human
Expression System: HEK293 Cells
UBE2J2 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01221
Species: Human
Expression System: E. coli
P3H 1 Protein, Streptomyces sp., Recombinant (His & Myc)
Cat.No: TMPH-03606
Species: Streptomyces
Expression System: E. coli
TRPV2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03390
Species: Rat
Expression System: E. coli
TRAIL Trimer Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00171
Species: Human
Expression System: HEK293 Cells
SCN1A Protein, Human, Recombinant (His)
Cat.No: TMPH-02118
Species: Human
Expression System: E. coli
GLTP Protein, Human, Recombinant (His)
Cat.No: TMPY-05003
Species: Human
Expression System: HEK293 Cells
Kallikrein 2/KLK2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00891
Species: Human
Expression System: HEK293 Cells
CLIC5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01363
Species: Human
Expression System: E. coli
JC polyomavirus (JCV) Minor capsid protein VP2 (His)
Cat.No: TMPH-02365
Species: JCPyV
Expression System: E. coli
Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His)
Cat.No: TMPH-02347
Species: H1N1
Expression System: E. coli
Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc)
Cat.No: TMPH-02348
Species: H1N1
Expression System: E. coli
VPS35 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02301
Species: Human
Expression System: E. coli
Hamster polyomavirus (HaPyV) VP1 Protein (His & Myc)
Cat.No: TMPH-00789
Species: HaPyV
Expression System: E. coli
BK polyomavirus (BKPyV) VP2 Protein (His)
Cat.No: TMPH-00201
Species: BKPyV
Expression System: E. coli
Enoyl-ACP Reductase Protein, E. coli, Recombinant (His)
Cat.No: TMPY-01812
Species: E. coli
Expression System: E. coli
NRROS Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02803
Species: Mouse
Expression System: E. coli
FCGRT Protein, Human, Recombinant (His)
Cat.No: TMPH-01516
Species: Human
Expression System: HEK293 Cells
FCGRT Protein, Human, Recombinant (GST)
Cat.No: TMPH-01517
Species: Human
Expression System: E. coli
UBE2L6 Protein, Human, Recombinant (His)
Cat.No: TMPY-02842
Species: Human
Expression System: E. coli
Amyloid Precursor Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00782
Species: Human
Expression System: HEK293 Cells
CSNK1G1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04402
Species: Human
Expression System: Baculovirus Insect Cells
JNK1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04554
Species: Human
Expression System: Baculovirus Insect Cells
MCP-4 Protein, Human, Recombinant (His)
Cat.No: TMPY-00564
Species: Human
Expression System: P. pastoris (Yeast)
Rac1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-01187
Species: Human
Expression System: Baculovirus Insect Cells
DNA-binding protein H-NS Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00616
Species: E. coli
Expression System: E. coli
Cat. No. Product Name Target Signaling Pathways
T60016 VV116

GS-621763-d1,JT001

SARS-CoV; RSV Microbiology/Virology
VV116 (JT001) 是一种针对呼吸道合胞病毒和 SARS-CoV-2 感染的选择性和口服活性核苷抗病毒剂。
T22301 L-838417 D9

CTP354,CTP354 (C-21191),C-21191

GABA Receptor Membrane transporter/Ion channel; Neuroscience
L-838417 D9 (C-21191) 是 L-838417 的氘代物。其中L-838417 是亚型选择性GABAA 正变构调节剂,在 α2, α3 和 α5 亚型中作为部分激动剂。
T14687 Deucravacitinib

BMS-986165

Tyrosine Kinases; JAK; IFNAR; Interleukin Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Deucravacitinib (BMS-986165) 是一种高选择性、口服生物可利用的变构 TYK2 抑制剂,用于治疗自身免疫性疾病。它通过稳定调节 JH2 结构域来阻断受体介导的 Tyk2 激活,可抑制IL-12/23和 I 型IFN 途径。它选择性结合 TYK2 假激酶 (JH2) 结构域,IC50为1.0 nM。
T11067 VX-984

M9831

DNA-PK DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
VX-984 (M9831) 是一种可口服的、具有选择性的的、可透过血脑屏障的 DNA-PK 抑制剂。VX-984 对非同源性末端 NHEJ 的接合具有抑制作用,可作用于 DSBs 使 DNA 双链断裂。VX-984常见于对胶质母细胞瘤 (GBM) 和非小细胞肺癌 (NSC-LC) 的研究。
T24046 WNK-IN-11-d3

WNK inhibitor-12,WNKIN12,WNK IN 12,WNK inhibitor 12,WNK-IN-12

WNK-IN-12 is an effective, selective, and orally active WNK1 kinase inhibitor.
T70332 JNJ-61393215

JNJ-61393215 is a novel selective orexin-1 receptor (OX1R) antagonist.
T26871 BMT-052

BMT052

BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).
T12571 PSI-6206 13C,d3

Sofosbuvir metabolite GS-331007 13CD3,RO-2433 13CD3,PSI-6206 13CD3,GS-331007 13CD3

Others Others
PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.
T13181 Tolcapone D7

Ro 40-7592 D7

Transferase Metabolism
Tolcapone D7 is a deuterium-labeled Tolcapone. Tolcapone is a selective and orally active inhibitor of COMT.
T11270 Febuxostat D9

非布司他D9

Others Others
Febuxostat D9 is deuterium labeled Febuxostat, which is a selective xanthine oxidase inhibitor with Ki of 0.6 nM.
T11610 Idelalisib D5

CAL-101 D5,GS-1101 D5

PI3K PI3K/Akt/mTOR signaling
Idelalisib D5 is a deuterium-labeled Idelalisib. Idelalisib is a highly selective and orally bioavailable p110δ inhibitor.
T12355 Palbociclib-d8

PD 0332991 D8,Palbociclib D8

CDK Cell Cycle/Checkpoint
Palbociclib D8 is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active inhibitor of CDK4 and CDK6 (IC50s of 11 and 16 nM, respectively).
T13137 TGFβRI-IN-1

TGF-beta/Smad Stem Cells
TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively ).
T12208 Nepafenac-d5

奈帕芬胺 D5,AHR-9434 D5,AL-6515 D5

Others Others
Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .
T10279 Alfacalcidol-D6

Others Others
Alfacalcidol-D6 is a deuterated Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.
T31109 CTP-499

CTP499, a selective PDE inhibitor, and the deuterium-containing agent is an HDX analogue and a metabolite of hexantheobromine that slows the progression of type 2 diabetic nephropathy in patients with macroalbuminuria.
T10527 Betrixaban-d6

Betrixaban D6

Others Others
Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.
T10288 Alogliptin (13CD3)

SYR-322 (13CD3)

Others Others
Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.
T12176 Naratriptan D3 Hydrochloride

GR-85548A D3

Others Others
Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.
T12671 (Rac)-Mirabegron-d5

(Rac)-Mirabegron D5,(Rac)-YM178 D5

Others Others
(Rac)-Mirabegron D5 is a deuterium labeled (Rac)-Mirabegron. Mirabegron is a selective agonist of β3-adrenoceptor.
T12329 Ospemifene D4

FC-1271a D4

Estrogen/progestogen Receptor Endocrinology/Hormones
Ospemifene D4 is a deuterium labeled Ospemifene. Ospemifene is a selective and orally active modulator of estrogen receptor.
T12227 Nimesulide D5

COX Immunology/Inflammation; Neuroscience
Nimesulide D5 is a deuterium labeled Nimesulide. Nimesulide is a selective inhibitor OF COX-2(IC50s of 70 nM-70 μM)
T13076 Tamoxifen-​d5

ICI 47699-​d5,(Z)-Tamoxifen-​d5,trans-Tamoxifen-​d5

HSP Cytoskeletal Signaling; Metabolism
Tamoxifen-d5 is a deuterium labeled Tamoxifen. Tamoxifen is a selective modulator of estrogen receptor (SERM). Tamoxifen is a potent activator of Hsp90 and enhances the Hsp90 molecular chaperone ATPase activity.
T10528 Bexarotene D4

LGD1069 D4

Others Others
Bexarotene D4 is a deuterium-labeled Bexarotene (LGD1069). Bexarotene is a selective RXR agonist used in the treatment of cutaneous T-cell lymphoma.
T12736 Rivaroxaban-d4

BAY 59-7939 D4

Factor Xa Metabolism
Rivaroxaban D4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent,selective and direct inhibitor of Factor Xa (FXa)(IC50:0.7 nM; Ki:0.4 nM).
T12167 Nadolol-d9

纳多洛尔 D9,SQ-11725 D9,Nadolol D9

Others Others
Nadolol D9 is the deuterium labeled Nadolol is a blocker of non-selective beta.
T70615 TAS-303

TAS-303 is a selective norepinephrine reuptake inhibitor which displays significant norepinephrine transporter (NET) inhibitory activity toward serotonin or dopamine transporters. Radioligand-binding studies showed that TAS-303 selectively and potently inhibited [3H]norepinephrine binding to the human NET.
T12023 Mexiletine-d6 hydrochloride

KOE-1173 D6 hydrochloride,Mexiletine D6 hydrochloride

Others Others
Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.
T12210 Netupitant D6

CID-6451149 D6

Others Others
Netupitant D6 is the deuterium labeled Netupitant, which is a selective and orally active antagonist of neurokinin-1 receptor.
TMIJ-0122 Mosapride-d5

Mosapride-d5 是 Mosapride 的氘代化合物。Mosapride 的 CAS 号为 112885-41-3。Mosapride是一种促胃肠动力药,是选择性5HT4激动剂。
TMIJ-0478 Pirimicarb-d6 (dimethylcarbamate-d6)

Pirimicarb-d6 (dimethylcarbamate-d6) 是 Pirimicarb 的氘代化合物。Pirimicarb 的 CAS 号为 23103-98-2。
TMID-0197 Metoprolol-d6

Metoprolol-d6 是 Metoprolol 的氘代化合物。Metoprolol 的 CAS 号为 51384-51-1。
T70394 Deucravacitinib HCl

Deucravacitinib HCl is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease. MS-986165 potently binds to the Tyk2 pseudokinase domain (Ki = 0.02 nM), and is highly selective against a panel of 265 kinases and pseudokinases. The compound potently inhibited IL-23-, IL-12-, and Type I interferon-driven cellular signaling and transcriptional resp...
T10950 Dabigatran D4 hydrochloride

BIBR-953 D4 hydrochloride

Others Others
Dabigatran D4 hydrochloride is deuterium-labeled dabigatran, which is a reversible and selective direct thrombin inhibitor (DTI) with a Ki value of 4.5 nM.
T73713 Flupirtine-d4 hydrochloride

Flupirtine-d4 (D 9998-d4) hydrochloride,Flupirtine (D 9998) hydrochloride的氘代物,为神经元钾通道开放剂,具有拮抗NMDA受体的作用。
T10229 Acebutolol D7

Others Others
Acebutolol D7 is a deuterium-labeled Acebutolol. Acebutolol is a selective antagonist of the β1 adrenergic receptor used in the treatment of angina pectoris, hypertension, and cardiac arrhythmias.
T11246 Etoricoxib-d4

MK-0663 D4,依托考昔 D4,L-791456 D4,Etoricoxib D4

Others Others
Etoricoxib D4 is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.Etoricoxib D4 is a deuterium labeled Etoricoxib.
TMIJ-0475 Terbuthylazine-d5 (ethyl-d5)

Terbuthylazine-d5 (ethyl-d5) 是 Terbuthylazine 的氘代化合物。Terbuthylazine 的 CAS 号为 5915-41-3。
T70174 Pirlindole-d4 HCl

Pirlindole-d4 is intended for use as an internal standard for the quantification of pirlindole by GC- or LC-MS. Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor. It is selective for MAO-A over MAO-B. In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackieviru...
TMID-0035 Naratriptan-d3

Naratriptan-d3 是 Naratriptan 的氘代化合物。Naratriptan 的 CAS 号为 121679-13-8。Naratriptan是一种5-HT1受体选择性激动剂,可作用于偏头疼。
T11995 Melatonin-d4

N-Acetyl-5-methoxytryptamine D5,Melatonin D5,褪黑素 D5

Others Others
Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulation. Additionally, it activates melatonin receptors and exhibits antioxidative and anti-inflammatory properties.
TMIJ-0336 Imidafenacin-d10

Imidafenacin-d10 是 Imidafenacin 的氘代化合物。Imidafenacin 的 CAS 号为 170105-16-5。Imidafenacin 是一种有效的和选择性的M3受体抑制剂,Kb值为0.317nM。
TMIJ-0499 Granisetron-d3

Granisetron-d3 是 Granisetron 的氘代化合物。Granisetron 的 CAS 号为 109889-09-0。
TMIJ-0242 Tandospirone-d8

Tandospirone-d8 是 Tandospirone 的氘代化合物。Tandospirone 的 CAS 号为 87760-53-0。
TMIJ-0338 Pitolisant-d6 HCl

Pitolisant-d6 HCl 是 Pitolisant HCl 的氘代化合物。Pitolisant HCl 的 CAS 号为 903576-44-3。Pitolisant hydrochloride 是一种有效的、选择性的组胺 H3 受体反向激动剂,Ki为0.16 nM。
TMIJ-0148 Avanafil-13C-d3

Avanafil-13C-d3 是 Avanafil 的 13C 和氘代化合物。Avanafil 的 CAS 号为 330784-47-9。Avanafil 是一种高活性PDE-5抑制剂,IC50=5.2 nM,对PDE1,PDE6和PDE11活性较低。
TMIJ-0480 Terbutryn-d5 (ethyl-d5)

Terbutryn-d5 (ethyl-d5) 是 Terbutryn 的氘代化合物。Terbutryn 的 CAS 号为 886-50-0。Terbutryn 是选择性除草剂和三嗪化合物,能够被根部和叶子吸收,抑制光合作用的发生。
TMID-0280 Atehexal-d7

Atehexal-d7 是 Atehexal 的氘代化合物。Atehexal 的 CAS 号为 29122-68-7。Atenolol 是一种心脏选择性的 β1 肾上腺素能受体 (β1-adrenergic receptor) 阻断剂,可用于研究高血压和心绞痛。它在豚鼠左心室膜β1肾上腺素能受体处的Ki为 697 nM。
TMID-0186 Fluvoxamine-d3 Maleate

Fluvoxamine-d3 Maleate 是 Fluvoxamine Maleate 的氘代化合物。Fluvoxamine Maleate 的 CAS 号为 61718-82-9。Fluvoxamine maleate 是一种5-羟色胺再吸收抑制剂,有抗抑郁作用。
TMIH-0330 Mesotrione-d3

Mesotrione-d3 是 Mesotrione 的氘代化合物。Mesotrione 的 CAS 号为 104206-82-8。Mesotrione 是一种苯甲酰环己二酮类除草剂,是一种竞争性羟基苯基丙酮酸双加氧酶酶抑制剂。它对玉米作物具有选择性,它在易感作物中代谢速度快,耐受性较高。
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同位素标记化合物

VV116
Cat.No: T60016
Synonym: GS-621763-d1,JT001
Target: SARS-CoV, RSV
L-838417 D9
Cat.No: T22301
Synonym: CTP354,CTP354 (C-21191),C-21191
Target: GABA Receptor
Deucravacitinib
Cat.No: T14687
Synonym: BMS-986165
Target: Tyrosine Kinases, JAK, IFNAR, Interleukin
VX-984
Cat.No: T11067
Synonym: M9831
Target: DNA-PK
WNK-IN-11-d3
Cat.No: T24046
Synonym: WNK inhibitor-12,WNKIN12,WNK IN 12,WNK inhibitor 12,WNK-IN-12
Target:
JNJ-61393215
Cat.No: T70332
Synonym:
Target:
BMT-052
Cat.No: T26871
Synonym: BMT052
Target:
PSI-6206 13C,d3
Cat.No: T12571
Synonym: Sofosbuvir metabolite GS-331007 13CD3,RO-2433 13CD3,PSI-6206 13CD3,GS-331007 13CD3
Target: Others
Tolcapone D7
Cat.No: T13181
Synonym: Ro 40-7592 D7
Target: Transferase
Febuxostat D9
Cat.No: T11270
Synonym: 非布司他D9
Target: Others
Idelalisib D5
Cat.No: T11610
Synonym: CAL-101 D5,GS-1101 D5
Target: PI3K
Palbociclib-d8
Cat.No: T12355
Synonym: PD 0332991 D8,Palbociclib D8
Target: CDK
TGFβRI-IN-1
Cat.No: T13137
Synonym:
Target: TGF-beta/Smad
Nepafenac-d5
Cat.No: T12208
Synonym: 奈帕芬胺 D5,AHR-9434 D5,AL-6515 D5
Target: Others
Alfacalcidol-D6
Cat.No: T10279
Synonym:
Target: Others
CTP-499
Cat.No: T31109
Synonym:
Target:
Betrixaban-d6
Cat.No: T10527
Synonym: Betrixaban D6
Target: Others
Alogliptin (13CD3)
Cat.No: T10288
Synonym: SYR-322 (13CD3)
Target: Others
Naratriptan D3 Hydrochloride
Cat.No: T12176
Synonym: GR-85548A D3
Target: Others
(Rac)-Mirabegron-d5
Cat.No: T12671
Synonym: (Rac)-Mirabegron D5,(Rac)-YM178 D5
Target: Others
Ospemifene D4
Cat.No: T12329
Synonym: FC-1271a D4
Target: Estrogen/progestogen Receptor
Nimesulide D5
Cat.No: T12227
Synonym:
Target: COX
Tamoxifen-​d5
Cat.No: T13076
Synonym: ICI 47699-​d5,(Z)-Tamoxifen-​d5,trans-Tamoxifen-​d5
Target: HSP
Bexarotene D4
Cat.No: T10528
Synonym: LGD1069 D4
Target: Others
Rivaroxaban-d4
Cat.No: T12736
Synonym: BAY 59-7939 D4
Target: Factor Xa
Nadolol-d9
Cat.No: T12167
Synonym: 纳多洛尔 D9,SQ-11725 D9,Nadolol D9
Target: Others
TAS-303
Cat.No: T70615
Synonym:
Target:
Mexiletine-d6 hydrochloride
Cat.No: T12023
Synonym: KOE-1173 D6 hydrochloride,Mexiletine D6 hydrochloride
Target: Others
Netupitant D6
Cat.No: T12210
Synonym: CID-6451149 D6
Target: Others
Mosapride-d5
Cat.No: TMIJ-0122
Synonym:
Target:
Pirimicarb-d6 (dimethylcarbamate-d6)
Cat.No: TMIJ-0478
Synonym:
Target:
Metoprolol-d6
Cat.No: TMID-0197
Synonym:
Target:
Deucravacitinib HCl
Cat.No: T70394
Synonym:
Target:
Dabigatran D4 hydrochloride
Cat.No: T10950
Synonym: BIBR-953 D4 hydrochloride
Target: Others
Flupirtine-d4 hydrochloride
Cat.No: T73713
Synonym:
Target:
Acebutolol D7
Cat.No: T10229
Synonym:
Target: Others
Etoricoxib-d4
Cat.No: T11246
Synonym: MK-0663 D4,依托考昔 D4,L-791456 D4,Etoricoxib D4
Target: Others
Terbuthylazine-d5 (ethyl-d5)
Cat.No: TMIJ-0475
Synonym:
Target:
Pirlindole-d4 HCl
Cat.No: T70174
Synonym:
Target:
Naratriptan-d3
Cat.No: TMID-0035
Synonym:
Target:
Melatonin-d4
Cat.No: T11995
Synonym: N-Acetyl-5-methoxytryptamine D5,Melatonin D5,褪黑素 D5
Target: Others
Imidafenacin-d10
Cat.No: TMIJ-0336
Synonym:
Target:
Granisetron-d3
Cat.No: TMIJ-0499
Synonym:
Target:
Tandospirone-d8
Cat.No: TMIJ-0242
Synonym:
Target:
Pitolisant-d6 HCl
Cat.No: TMIJ-0338
Synonym:
Target:
Avanafil-13C-d3
Cat.No: TMIJ-0148
Synonym:
Target:
Terbutryn-d5 (ethyl-d5)
Cat.No: TMIJ-0480
Synonym:
Target:
Atehexal-d7
Cat.No: TMID-0280
Synonym:
Target:
Fluvoxamine-d3 Maleate
Cat.No: TMID-0186
Synonym:
Target:
Mesotrione-d3
Cat.No: TMIH-0330
Synonym:
Target:
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