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FFN 102 mesylate 是pH 响应型荧光假神经递质(FFN),作为选择性多巴胺转运蛋白(DAT)和VMAT2底物。FFN 102 mesylate 与38个中枢神经系统受体(包括多巴胺和血清素受体)无明显结合。它的Ex-max在pH 值5时为340 nm,在pH 值7.5时为370 nm,在pH 值为5和7.5时,Em-max为435 nm。
FFN 102 mesylate 是pH 响应型荧光假神经递质(FFN),作为选择性多巴胺转运蛋白(DAT)和VMAT2底物。FFN 102 mesylate 与38个中枢神经系统受体(包括多巴胺和血清素受体)无明显结合。它的Ex-max在pH 值5时为340 nm,在pH 值7.5时为370 nm,在pH 值为5和7.5时,Em-max为435 nm。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 203 | 现货 | |
5 mg | ¥ 472 | 现货 | |
10 mg | ¥ 702 | 现货 | |
25 mg | ¥ 1,180 | 现货 | |
50 mg | ¥ 1,750 | 现货 | |
100 mg | ¥ 2,500 | 现货 | |
200 mg | ¥ 3,560 | 现货 |
产品描述 | FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN), a selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.FFN 102 mesylate is a Ph-responsive fluorescent pseudoneurotransmitter (FFN) that acts as a substrate for selective dopamine transporters (DAT) and VMAT2. |
体外活性 | FFN102的吸收光谱显示出pH依赖性:在较低pH值时,吸收峰向331 nm移动;而在较高pH值时,吸收峰向371 nm移动,分别对应于质子化和去质子化形态[1]。 |
别名 | FFN 102甲磺酸盐 |
分子量 | 335.76 |
分子式 | C12H14ClNO6S |
CAS No. | 1883548-92-2 |
Smiles | O=C1OC=2C=C(O)C(Cl)=CC2C(=C1)CCN.O=S(=O)(O)C |
存储 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 45 mg/mL (134.02 mM), Sonication is recommended. H2O: 6.0 mg/mL (18.0 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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