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N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM). It inhibits serotonin uptake in rat brain synaptosomes with an IC50 value of 22 nM. N-methyl Paroxetine has been used as a precursor in the synthesis of paroxetine and is a potential impurity in commercial preparations of paroxetine.
N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM). It inhibits serotonin uptake in rat brain synaptosomes with an IC50 value of 22 nM. N-methyl Paroxetine has been used as a precursor in the synthesis of paroxetine and is a potential impurity in commercial preparations of paroxetine.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 mg | 待估 | 35日内发货 | |
1 g | 待估 | 35日内发货 | |
5 g | 待估 | 35日内发货 |
产品描述 | N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM). It inhibits serotonin uptake in rat brain synaptosomes with an IC50 value of 22 nM. N-methyl Paroxetine has been used as a precursor in the synthesis of paroxetine and is a potential impurity in commercial preparations of paroxetine. |
分子量 | 343.39 |
分子式 | C20H22FNO3 |
CAS No. | 110429-36-2 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | Ethanol: 20 mg/mL (58.24 mM), Sonication is recommended. DMF:PBS (pH 7) (1:10): 0.09 mg/mL (0.26 mM), Sonication is recommended. DMSO: 20 mg/mL (58.24 mM), Sonication is recommended. DMF: 33 mg/mL (96.1 mM), Sonication is recommended. |
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