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(R,R)-CXCR2-IN-2, diastereoisomer of CXCR2-IN-2 (compound 68), is a brain penetrant CXCR2 antagonist with a pIC50 of 9 and 6.8 in the Tango assay and d in the HWB Gro-α induced CD11b expression assay, respectively[1].
(R,R)-CXCR2-IN-2, diastereoisomer of CXCR2-IN-2 (compound 68), is a brain penetrant CXCR2 antagonist with a pIC50 of 9 and 6.8 in the Tango assay and d in the HWB Gro-α induced CD11b expression assay, respectively[1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 4,160 | 8-10周 | |
25 mg | ¥ 15,000 | 8-10周 | |
50 mg | ¥ 19,800 | 8-10周 | |
100 mg | ¥ 25,500 | 8-10周 | |
1 mL x 10 mM (in DMSO) | ¥ 4,980 | 8-10周 |
产品描述 | (R,R)-CXCR2-IN-2, a diastereoisomer of CXCR2-IN-2 (compound 68), functions as a brain-penetrant CXCR2 antagonist. It exhibits a pIC50 of 9 in the Tango assay and 6.8 in the HWB Gro-α induced CD11b expression assay[1]. |
别名 | (R,R)-CXCR2-IN-2 |
分子量 | 414.9 |
分子式 | C18H23ClN2O5S |
CAS No. | 1838123-22-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 220 mg/mL (530.25 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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