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UNC2399, a biotinylated version of UNC1999, functions as a selective degrader of EZH2 and exhibits strong in vitro efficacy against EZH2, demonstrated by its IC 50 value of 17 nM.
UNC2399, a biotinylated version of UNC1999, functions as a selective degrader of EZH2 and exhibits strong in vitro efficacy against EZH2, demonstrated by its IC 50 value of 17 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 4,750 | 期货 |
产品描述 | UNC2399, a biotinylated version of UNC1999, functions as a selective degrader of EZH2 and exhibits strong in vitro efficacy against EZH2, demonstrated by its IC 50 value of 17 nM. |
靶点活性 | EZH2:17 nM (IC50) |
体外活性 | UNC2399 (1-1000 nM) displays high in vitro potency (IC 50 =17±2 nM) in the EZH2 radioactive biochemical assay[1]. UNC2399 (100 μM) enriches EZH2 from HEK293T cell lysates[1]. |
别名 | UNC2399 |
分子量 | 1353.68 |
分子式 | C67H104N10O17S |
CAS No. | 2412791-72-9 |
密度 | 1.29 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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