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Docebenone
还可以产品编号 T15155Cas号 80809-81-0
别名 AA 861
Docebenone is a selective and orally active inhibitor of 5-LO.
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Docebenone
还可以产品编号 T15155 别名 AA 861Cas号 80809-81-0
Docebenone is a selective and orally active inhibitor of 5-LO.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 3,190 | 5日内发货 | |
| 5 mg | ¥ 3,730 | 5日内发货 | |
| 25 mg | ¥ 13,400 | 8-10周 | |
| 50 mg | ¥ 17,500 | 8-10周 | |
| 100 mg | ¥ 24,600 | 8-10周 | |
| 1 mL x 10 mM (in DMSO) | ¥ 4,120 | 5日内发货 |
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产品介绍
生物活性
化学信息
| 产品描述 | Docebenone is a selective and orally active inhibitor of 5-LO. |
| 体外活性 | Docebenone strongly abolishes the stimulatory effect of TvSP on IL-8 production. Treatment of trichomonads with the 5-LO inhibitor Docebenone, significantly inhibits the ability of trichomonads to secrete LTB4 compared to results for trichomonads treated with the medium [1]. Docebenone at 10-200 μM increases [Ca2+]i concentration-dependently [2]. |
| 体内活性 | In monkeys, Docebenone (0.01-10 μM) suppresses the release of SRS-A by 55-97% with a dose-dependently manner. The antigen-induced SRS-A release from these fragments is dose-dependently inhibited by 25-93% of Docebenone (0.01-10 μM) [4]. Docebenone may protect experimental acute necrotizing pancreatitis in rats [3]. |
| 别名 | AA 861 |
| 分子量 | 326.43 |
| 分子式 | C21H26O3 |
| CAS No. | 80809-81-0 |
| 密度 | no data available |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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