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Ro 363 hydrochloride 是一种有效的,高度选择性的 β1 肾上腺素受体 (β1-adrenoceptor) 激动剂。Ro 363 hydrochloride 是有效的正性肌力活化剂。Ro 363 hydrochloride 是心血管调节剂,可降低舒张压,显著增加心肌收缩力。
Ro 363 hydrochloride 是一种有效的,高度选择性的 β1 肾上腺素受体 (β1-adrenoceptor) 激动剂。Ro 363 hydrochloride 是有效的正性肌力活化剂。Ro 363 hydrochloride 是心血管调节剂,可降低舒张压,显著增加心肌收缩力。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 1,370 | 5日内发货 | |
100 mg | ¥ 10,951 | 6-8周 |
产品描述 | Ro 363 hydrochloride is an effective, highly selective agonist of β 1-adrenoceptor. Ro 363 hydrochloride is an effective inotropic stimulant. Ro 363 hydrochloride is a cardiovascular regulator, which can reduce diastolic blood pressure and significantly increase myocardial contractility. |
体外活性 | Isolated perfused heart preparations from guinea-pigs developed arrhythmic contractions following the administration of Ro 363 in doses producing 70-100% of its maximal chronotropic responses [1]. In spontaneously contracted tracheal preparations from the guinea-pig, RO 363 is a full agonist and is approximately half as potent as (-)-Isoprenaline. These effects of RO 363 are due to the activation of a population of β1-receptors in the tissue since RO 363 and (-)-Isoprenaline have the same relative potencies in trachea, cardiac and ileal preparations [2]. |
体内活性 | In chloralose-anaesthetized cats, Ro 363, when compared to epinephrine (adrenaline), is essentially devoid of arrhythmogenic activity in animals in which cardiac sensitization is induced by U-0882 or halothane [1]. |
分子量 | 399.87 |
分子式 | C19H26ClNO6 |
CAS No. | 250580-70-2 |
存储 | Shipping with blue ice. |
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