购物车
- 全部删除
- 您的购物车当前为空
MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)
MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 17,280 | 8-10周 | |
50 mg | ¥ 27,680 | 8-10周 | |
100 mg | ¥ 44,280 | 8-10周 |
产品描述 | MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM) |
靶点活性 | PTB1B:1 μM , TCPTP:224 μM |
体外活性 | Trodusquemine significantly enhanced insulin-stimulated tyrosine phosphorylation of insulin receptor (IR) beta and STAT3, direct targets of PTP1B, in HepG2 cells in vitro and/or hypothalamic tissue[1]. |
体内活性 | Trodusquemine (MSI-1436) causes rapid and reversible weight loss in genetic models of obesity.?Trodusquemine suppressed appetite, reduced body weight (BW) in a fat-specific manner, and improved plasma insulin and leptin levels in mice[1]. |
别名 | Trodusquemine, Aminosterol-1436 |
分子量 | 685.06 |
分子式 | C37H72N4O5S |
CAS No. | 186139-09-3 |
密度 | 1.12 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
评论内容