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CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM).
CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 13,650 | 8-10周 |
产品描述 | CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM). |
靶点活性 | CDK9:1.8 nM, CDK2:155 nM |
体外活性 | CDK9-IN-9 (example 2) inhibits the proliferation of HeLa, HeLa-MaTu-ADR, DU145, NCI-H460, Caco-2, B16F10, A2780 and MOLM-13 cells (IC50s: 4.4 nM, 5.3 nM, 4.5 nM, 9.2 nM, 8.4 nM, 1.2 nM, 1.2 nM, 2.0 nM). |
分子量 | 459.51 |
分子式 | C22H23F2N5O2S |
CAS No. | 2246956-84-1 |
密度 | 1.42 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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