DDR1-IN-5

Name: DDR1-IN-5
Brand: TargetMol
SKU: T40062
Price: 463 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T40062Cas号 2416022-90-5

别名 DDR1-IN-5

DDR1-IN-5 is a potent and selective inhibitor of the Discoidin Domain Receptor family, member 1 (DDR1). It effectively inhibits the phosphorylation of DDR1b (Y513) with an IC 50 value of 4.1 nM. Furthermore, DDR1-IN-5 demonstrates remarkable anti-cancer activity. Its inhibitory potency against DDR1 (IC 50 = 7.36 nM) makes it a promising compound for targeted therapy in cancer treatment.

DDR1-IN-5

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产品编号 T40062 别名 DDR1-IN-5Cas号 2416022-90-5

规格	价格	库存	数量
2 mg	¥ 3,420	5日内发货

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生物活性

产品描述	DDR1-IN-5 is a potent and selective inhibitor of the Discoidin Domain Receptor family, member 1 (DDR1). It effectively inhibits the phosphorylation of DDR1b (Y513) with an IC 50 value of 4.1 nM. Furthermore, DDR1-IN-5 demonstrates remarkable anti-cancer activity. Its inhibitory potency against DDR1 (IC 50 = 7.36 nM) makes it a promising compound for targeted therapy in cancer treatment.
靶点活性	DDR1:7.36 nM (IC50)
体外活性	DDR1-IN-5 (compound 121; for 24 hours) inhibits collagen production in human hepatic stellate cell LX-2 (IC 50 =62 nM)[1]. DDR1-IN-5 (72 hours) has cytotoxicity in LX-2 cells (CC 50 >40 μM)[1].
别名	DDR1-IN-5