Furamidine dihydrochloride

Name: Furamidine dihydrochloride
Brand: TargetMol
SKU: T27395
Rating: 4.5 (1 reviews)

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产品编号 T27395Cas号 55368-40-6

别名 Furamidine HCl, DB 75, DB75, NSC 305831, WR199385

Furamidine is a cell-permeable, selective inhibitor of protein arginine methyltransferase 1 (PRMT1). Furamidine binds to strings of AT base pair sequences in DNA′s minor groove. Furamidine targets the enzyme active site and is primarily competitive with the substrate and noncompetitive toward the cofactor. Furthermore, Furamidine blocks cell proliferation in leukemia cell lines with different genetic lesions.

Furamidine dihydrochloride

还可以

产品编号 T27395 别名 Furamidine HCl, DB 75, DB75, NSC 305831, WR199385Cas号 55368-40-6

规格	价格	库存
1 mg	¥ 560	35日内发货
5 mg	¥ 1,620	35日内发货
10 mg	¥ 2,950	35日内发货

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产品描述	Furamidine is a cell-permeable, selective inhibitor of protein arginine methyltransferase 1 (PRMT1). Furamidine binds to strings of AT base pair sequences in DNA′s minor groove. Furamidine targets the enzyme active site and is primarily competitive with the substrate and noncompetitive toward the cofactor. Furthermore, Furamidine blocks cell proliferation in leukemia cell lines with different genetic lesions.
靶点活性	PRMT1:9.4 μM (IC50), PRMT4:>400 µM (IC50), PRMT5:166 µM (IC50), PRMT6:283 µM (IC50)
别名	Furamidine HCl, DB 75, DB75, NSC 305831, WR199385