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GRKs-IN-1 hydrochloride, Compound 14as, has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50=130 nM) and GRK5 (IC50=7.1 μM).GRKs-IN-1 hydrochloride is a derivative 14as of paroxetine, shows a 100-fold improvement in cardiomyocyte contractility assays over paroxetine[1].
GRKs-IN-1 hydrochloride, Compound 14as, has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50=130 nM) and GRK5 (IC50=7.1 μM).GRKs-IN-1 hydrochloride is a derivative 14as of paroxetine, shows a 100-fold improvement in cardiomyocyte contractility assays over paroxetine[1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 939 | 期货 | |
2 mg | ¥ 1,587 | 期货 | |
5 mg | ¥ 2,802 | 期货 | |
10 mg | ¥ 4,422 | 期货 | |
25 mg | ¥ 7,986 | 期货 | |
50 mg | ¥ 13,332 | 期货 | |
100 mg | ¥ 18,192 | 期货 | |
1 mL x 10 mM (in DMSO) | ¥ 3,016 | 期货 |
产品描述 | GRKs-IN-1 hydrochloride, Compound 14as, has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50=130 nM) and GRK5 (IC50=7.1 μM).GRKs-IN-1 hydrochloride is a derivative 14as of paroxetine, shows a 100-fold improvement in cardiomyocyte contractility assays over paroxetine[1]. |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | H2O: 50 mg/mL (102.26 mM), Sonication is recommended. DMSO: 250 mg/mL (511.31 mM), Sonication is recommended. |
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