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ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 又称 EAPT,是一种有效的选择性 PDE4抑制剂,调节细胞内环腺苷酸(cAMP)水平。它已被用于多种科研应用,包括 cAMP 介导的信号转导通路的研究,并有潜力作为治疗炎症和免疫相关疾病的药物。
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ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 又称 EAPT,是一种有效的选择性 PDE4抑制剂,调节细胞内环腺苷酸(cAMP)水平。它已被用于多种科研应用,包括 cAMP 介导的信号转导通路的研究,并有潜力作为治疗炎症和免疫相关疾病的药物。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 125 | 现货 | |
5 mg | ¥ 273 | 现货 | |
10 mg | ¥ 410 | 现货 | |
25 mg | ¥ 703 | 现货 | |
50 mg | ¥ 1,050 | 现货 | |
100 mg | ¥ 1,580 | 现货 | |
200 mg | ¥ 2,360 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 239 | 现货 |
产品描述 | ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate, also known as EAPT, is a potent and selective PDE4 inhibitor that regulates intracellular cyclic adenosine monophosphate (cAMP) levels. It has been used in a variety of scientific applications, including the study of cAMP-mediated signaling pathways, and has potential as a therapeutic agent for the treatment of inflammatory and immune-related diseases. |
分子量 | 299.25 |
分子式 | C13H12F3N3O2 |
CAS No. | 223500-15-0 |
Smiles | C(F)(F)(F)C=1N(N=CC1C(OCC)=O)C2=CC=C(N)C=C2 |
密度 | 1.39 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 45 mg/mL (150.37 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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