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AA147 (ATF6-activator-147) 是小分子内质网蛋白稳态调节剂,能够选择性激活未折叠蛋白反应的 ATF6臂。
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AA147 (ATF6-activator-147) 是小分子内质网蛋白稳态调节剂,能够选择性激活未折叠蛋白反应的 ATF6臂。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 223 | 现货 | |
5 mg | ¥ 497 | 现货 | |
10 mg | ¥ 786 | 现货 | |
25 mg | ¥ 1,290 | 现货 | |
50 mg | ¥ 1,950 | 现货 | |
100 mg | ¥ 2,890 | 现货 | |
500 mg | ¥ 6,590 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 518 | 现货 |
产品描述 | AA147 (ATF6-activator-147) is a small molecule endoplasmic reticulum (ER) proteostasis regulator. The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially triggers ATF6 signaling through a mechanism involving localized metabolic activation and selective covalent modification of ER resident proteins that regulate ATF6 activity. |
别名 | ATF6-activator-147 |
分子量 | 255.31 |
分子式 | C16H17NO2 |
CAS No. | 393121-74-9 |
Smiles | Cc1ccc(O)c(NC(=O)CCc2ccccc2)c1 |
密度 | 1.190 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 25 mg/mL (97.92 mM) | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
DMSO
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