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10-DEBC hydrochloride 是选择性的Akt 抑制剂,IC50为 1.28 μM。10-DEBC hydrochloride 也是一种新型抗肺结核的化合物。
10-DEBC hydrochloride 是选择性的Akt 抑制剂,IC50为 1.28 μM。10-DEBC hydrochloride 也是一种新型抗肺结核的化合物。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 857 | 35日内发货 | |
5 mg | ¥ 2,360 | 35日内发货 | |
10 mg | ¥ 2,940 | 35日内发货 |
产品描述 | 10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2]. |
体外活性 | It is found that 10-DEBC inhibits the growth of Mtb in whole-cell assay with an IC 50 of 12.8 μM, while inhibiting replication of Mtb inside iMACs with an IC 50 of 1.5 μM, without host cell toxicity even at the highest concentration of 25 μM [2]. |
分子量 | 381.34 |
分子式 | C20H26Cl2N2O |
CAS No. | 925681-41-0 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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