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BAY 60-2770 is a selective and orally active soluble guanylyl cyclase (sGC) activator with antifibrotic effect. It increases the activity of sGC in a nitric oxide-independent manner.
BAY 60-2770 is a selective and orally active soluble guanylyl cyclase (sGC) activator with antifibrotic effect. It increases the activity of sGC in a nitric oxide-independent manner.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 692 | 5日内发货 | |
25 mg | ¥ 5,630 | 8-10周 | |
50 mg | ¥ 7,320 | 8-10周 | |
100 mg | ¥ 11,200 | 8-10周 |
产品描述 | BAY 60-2770 is a selective and orally active soluble guanylyl cyclase (sGC) activator with antifibrotic effect. It increases the activity of sGC in a nitric oxide-independent manner. |
体内活性 | BAY 60-2770 (0.1-0.3 mg/kg; p.o.) attenuates liver fibrosis in two rat models [1]. BAY 60-2770 (1 mg/kg; p.o.; daily from the 10th to the 12th week) results in amelioration of bladder dysfunction in high-fat obese mice [2]. |
分子量 | 623.63 |
分子式 | C35H33F4NO5 |
CAS No. | 1027642-43-8 |
密度 | 1.288 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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