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CDK-IN-14(Compound 9)作为一种高效的CDKL2(Cyclin-dependent kinase-like 2,类细胞周期蛋白依赖性激酶 2)选择性抑制剂,显示出460 nM的IC50值.由于CDKL2与肿瘤形成、发育及病毒感染等多个生物学过程有关,CDK-IN-14被视为探究CDKL2生物学功能的重要工具,并且在癌症和感染病理研究领域显示出应用潜力.
CDK-IN-14(Compound 9)作为一种高效的CDKL2(Cyclin-dependent kinase-like 2,类细胞周期蛋白依赖性激酶 2)选择性抑制剂,显示出460 nM的IC50值.由于CDKL2与肿瘤形成、发育及病毒感染等多个生物学过程有关,CDK-IN-14被视为探究CDKL2生物学功能的重要工具,并且在癌症和感染病理研究领域显示出应用潜力.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | CDK-IN-14 (Compound 9) serves as a potent and selective inhibitor of CDKL2 (Cyclin-dependent kinase-like 2), exhibiting an IC50 of 460 nM. Linked to biological processes such as tumor formation, development, and viral infections, CDKL2 is a substantial focus in the field. CDK-IN-14 holds promise as a powerful tool for the exploration of CDKL2s biological functions, potentially advancing research in areas like cancer and infectious diseases. |
体外活性 | CDK-IN-14 (0-4 μM, 1小时) 在大鼠初级神经元中通过抑制CDKL2,阻断了其介导的下游信号传导路径,显示出对CDKL2活性的强效抑制作用. |
分子量 | 426.53 |
分子式 | C22H26N4O3S |
CAS No. | 2471972-15-1 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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